In heavily irradiated mice, bone marrow regeneration of either endogenous or exogenous
origin was shown to occur in discrete foci comparable to the more intensively studied spleen …

The growth and differentiation of spleen colonies (discrete nodules of hemopoietic tissue
arising in the spleens of lethally irradiated mice given low doses of isogenic bone marrow …

Haematopoietic microenvironmental niches have been described as the 'gatekeepers' for
the blood and immune systems. These niches change during ontogeny, with the bone …

The polycythemic repression of erythropoiesis and the restoration of erythropoiesis by
specific stimulation were studied in the spleen colony system in irradiated mice. 1. A 5 day …

THE LYMPHOID SYSTEM and immunological functions are in their complete construction,
late developments in phylogeny. Similarly, the development of immunologic capacities, the …

The cellular composition of individual hemopoietic spleen colonies has been studied using
techniques which tested primarily for cell function rather than cell morphology. Erythroblastic …

The interesting history of over a century of knowledge of the bone marrow as the seedbed of
the blood, a seedbed in which migratory stem cells proliferate and differentiate, has been …

The progressive growth and development of spleen colonies was studied in heavily
irradiated host mice in which erythropoiesis was modified by various procedures …

This paper reports new data on the effect of the action of the mutant genes W and Wv on
murine hemopoiesis. Our studies demonstrate that the presence of these mutant genes …

A variety of erythropoietic stimuli influenced the number of endogenous spleen colonies in
irradiated mice and the number of transplantable colony forming cells in the spleen and …