The ongoing COVID-19 pandemic has resulted in millions of deaths globally, highlighting
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …

The COVID-19 pandemic has put healthcare infrastructures and our social and economic
lives under unprecedented strain. Effective solutions are needed to end the pandemic while …

Abstract Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), which enter the host cells through the interaction …

Pseudoviruses are viral particles coated with a heterologous envelope protein, which
mediates the entry of pseudoviruses as efficiently as that of the live viruses possessing high …

Since its inception, the coronavirus disease 2019 (COVID‐19) pandemic has infected
millions of people around the world. Therefore, it is necessary to find effective treatments …

Cepharanthine is an active ingredient separated and extracted from Stephania cepharantha
Hayata, a Menispermaceae plant. As a bisbenzylisoquinoline alkaloid, cepharanthine has …

The emergence of SARS-CoV-2 in December 2019 has become a global issue due to the
continuous upsurge in patients and the lack of drug efficacy for treatment. SARS-CoV-2 …

Benzylisoquinoline alkaloids (BIAs) are a structurally diverse group of plant specialized
metabolites found mainly in members of the order Ranunculales, including opium poppy …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of
approved drugs against acute viral diseases. Plants are considered inexhaustible sources of …

Recently, the inhibiting effects of a clinically approved drug Cepharanthine on severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) have attracted widespread attention and …