The rapid progress in the field of stem cell research has laid strong foundations for their use
in regenerative medicine applications of injured or diseased tissues. Growing evidences …

Tissue engineering has markedly matured since its early beginnings in the 1980s. In
addition to the original goal to regenerate damaged organs, the field has started to explore …

Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

Induced pluripotent stem cells (iPSCs) have the ability to differentiate into cardiomyocytes
(CMs). They are not only widely used in cardiac pharmacology screening, human heart …

Myocardial infarction caused by coronary artery obstruction results in the loss of heart
muscle, which is subsequently replaced by scar tissue with limited therapeutic options …

The versatility of pluripotent stem cells, attributable to their unlimited self-renewal capacity
and plasticity, has sparked a considerable interest for potential application in regenerative …

Although the clinical outcomes of cell therapy trials have not met initial expectations,
emerging evidence suggests that injury-mediated tissue damage might benefit from the …

Establishing an appropriate disease model that mimics the complexities of human
cardiovascular disease is critical for evaluating the clinical efficacy and translation success …

Cardiovascular disease is the leading cause of mortality and morbidity worldwide. Despite
improvements in the standard of care for patients with heart diseases, including innovation …

Recently, biomaterial scaffolds have been widely applied in the field of tissue engineering
and regenerative medicine. Due to different production methods, unique types of three …