Revival of leishmanization and leishmanin

T Pacheco-Fernandez, G Volpedo… - Frontiers in Cellular …, 2021 - frontiersin.org
Leishmaniasis includes a spectrum of diseases ranging from debilitating cutaneous to fatal
visceral infections. This disease is caused by the parasitic protozoa of the genus Leishmania …

Cytokines and signaling networks regulating disease outcomes in leishmaniasis

A Saha, S Roy, A Ukil - Infection and Immunity, 2022 - Am Soc Microbiol
Cytokines play crucial roles in commencing and coordinating the organized recruitment and
activation of immune cells during infection. These molecular regulators play an important …

A recombinant chimeric protein-based vaccine containing T-cell epitopes from amastigote proteins and combined with distinct adjuvants, induces immunogenicity and …

DP Lage, DL Vale, FP Linhares, CS Freitas… - Vaccines, 2022 - mdpi.com
Currently, there is no licensed vaccine to protect against human visceral leishmaniasis (VL),
a potentially fatal disease caused by infection with Leishmania parasites. In the current …

Effector functions of Th17 cells are regulated by IL‐35 and TGF‐β in visceral leishmaniasis

M Asad, A Sabur, M Kamran, M Shadab… - The FASEB …, 2021 - Wiley Online Library
Visceral leishmaniasis (VL) is a debilitating human pathogenesis in which the body's
immune functions are severely compromised. Various subsets of T cells, including Th17 …

Leishmania infantum amastin protein incorporated in distinct adjuvant systems induces protection against visceral leishmaniasis

PAF Ribeiro, DL Vale, DS Dias, DP Lage… - Cytokine, 2020 - Elsevier
The control measures against visceral leishmaniasis (VL) include a precise diagnosis of
disease, the treatment of human cases, and reservoir and vector controls. However, these …

Leishmania LiHyC protein is immunogenic and induces protection against visceral leishmaniasis

AS Machado, DP Lage, DL Vale, CS Freitas… - Parasite …, 2022 - Wiley Online Library
Abstract Treatment against visceral leishmaniasis (VL) presents problems by the toxicity of
drugs, high cost and/or emergence of resistant strains. The diagnosis is hampered by …

Th17 lymphocytes in atypical cutaneous leishmaniasis caused by Leishmania (L.) infantum chagasi in Central America

GV Araujo Flores, CM Sandoval Pacheco… - Parasite …, 2020 - Wiley Online Library
Skin lesions in nonulcerated cutaneous leishmaniasis (NUCL) caused by Leishmania (L.)
infantum chagasi are characterized by a mononuclear inflammatory infiltrate in the dermis …

[HTML][HTML] Lipophosphoglycan-3 protein from Leishmania infantum chagasi plus saponin adjuvant: A new promising vaccine against visceral leishmaniasis

S de Oliveira Emerick, TV de Carvalho, BM Miranda… - Vaccine, 2021 - Elsevier
Visceral leishmaniasis (VL) is a serious neglected tropical disease that affects humans and
dogs in urban areas. There are no vaccines against human VL, and few licensed canine VL …

Recombinant endonuclease III protein from Leishmania infantum associated with Th1-type adjuvants is immunogenic and induces protection against visceral …

DP Lage, AS Machado, CS Freitas, DL Vale… - Molecular …, 2023 - Elsevier
Vaccination against visceral leishmaniasis (VL) should be considered as a safe and
effective measure to disease control; however, few vaccines are available against canine VL …

[HTML][HTML] Immunostimulatory role of rBmHSP60 from filarial parasite Brugia malayi

V Kushwaha, S Kaur - Asian Pacific Journal of Tropical …, 2021 - journals.lww.com
Objective: To evaluate the immunostimulatory potential of cross-reactive molecule heat
shock protein 60 (HSP60) of filarial parasite Brugia malayi and Leishmania donovani …