Acinetobacter baumannii Infections in Times of COVID-19 Pandemic

K Rangel, TPG Chagas, SG De-Simone - Pathogens, 2021 - mdpi.com
The COVID-19 pandemic has generated an overuse of antimicrobials in critically ill patients.
Acinetobacter baumannii frequently causes nosocomial infections, particularly in intensive …

Hospital-acquired infections caused by enterococci: A systematic review and meta-analysis, WHO European Region, 1 January 2010 to 4 February 2020

S Brinkwirth, O Ayobami, T Eckmanns… - …, 2021 - eurosurveillance.org
Background Hospital-acquired infections (HAI) caused by Enterococcus spp., especially
vancomycin-resistant Enterococcusspp.(VRE), are of rising concern. Aim We summarised …

Antimicrobial resistance rates and surveillance in sub-Saharan Africa: where are we now?

S Kariuki, K Kering, C Wairimu, R Onsare… - Infection and drug …, 2022 - Taylor & Francis
Introduction Although antimicrobials have traditionally been used to treat infections and
improve health outcomes, resistance to commonly used antimicrobials has posed a major …

Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics

PE Klebba, SMC Newton, DA Six, A Kumar… - Chemical …, 2021 - ACS Publications
Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

[HTML][HTML] Factors mediating Acinetobacter baumannii biofilm formation: Opportunities for developing therapeutics

K Upmanyu, QMR Haq, R Singh - Current Research in Microbial Sciences, 2022 - Elsevier
Acinetobacter baumannii has notably become a superbug due to its mounting risk of
infection and escalating rates of antimicrobial resistance, including colistin, the last-resort …

Structure of a Rhs effector clade domain provides mechanistic insights into type VI secretion system toxin delivery

BK Hayes, M Harper, H Venugopal, JM Lewis… - Nature …, 2024 - nature.com
The type VI secretion system (T6SS) is a molecular machine utilised by many Gram-negative
bacteria to deliver antibacterial toxins into adjacent cells. Here we present the structure of …

A Comparison of Colistin versus Colistin Plus Meropenem for the Treatment of Carbapenem-Resistant Acinetobacter baumannii in Critically Ill Patients: A Propensity …

W Katip, S Uitrakul, P Oberdorfer - Antibiotics, 2020 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii (CRAB), an important nosocomial
pathogen, occurs particularly in the intensive care unit (ICU). Thus, the aim of this study was …

Impact of difficult-to-treat resistance in gram-negative bacteremia on mortality: retrospective analysis of nationwide surveillance data

K Huh, DR Chung, YE Ha, JH Ko… - Clinical Infectious …, 2020 - academic.oup.com
Background Clinically relevant categorization of antimicrobial resistance is critical to
mitigating the threat it poses. Difficult-to-treat resistance (DTR) is a recently proposed …

Mapping and gap analysis on antimicrobial resistance surveillance systems in Kenya, Tanzania, Uganda and Zambia

M Matee, SE Mshana, M Mtebe, EV Komba… - Bulletin of the National …, 2023 - Springer
Background Antimicrobial resistance is a global problem and involve pathogens which have
the potential to move between food producing animals and humans by direct exposure or …

Application of Antimicrobial Photodynamic Therapy for Inactivation of Acinetobacter baumannii Biofilms

I Buchovec, E Vyčaitė, K Badokas… - International Journal of …, 2022 - mdpi.com
Acinetobacter baumannii is a dangerous hospital pathogen primarily due to its ability to form
biofilms on different abiotic and biotic surfaces. The present study investigated the effect of …