Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …

All forms of life maintain a reducing environment (homeostasis) within their cells.
Perturbations in the normal redox state can lead to an oxidative environment which has …

A series of new bis-1, 2, 3-triazole linked ciprofloxacin conjugates was designed,
synthesized and evaluated in vitro antibacterial activity against a panel of clinically relevant …

Thiosemicarbazones (TSCNs) constitute a broad family of compounds (R1R2C= N-NH-C (S)-
NR3R4), particularly attractive because many of them display some biological activity …

Some biologically active semicarbazone-triazole hybrid molecules have been designed and
synthesized from semicarbazone linked terminal alkyne and aromatic azides via Cu (I) …

In order to discover novel anti-inflammatory agents, three series of compounds obtained by
appending 1, 2, 3-triazole moieties on ursolic acid were designed and synthesized. All …

Candida is an important opportunistic human fungal pathogen. The cis-2-dodecenoic acid
(BDSF) showing in vitro activity of against C. albicans growth, germ-tube germination and …

Obesity and dyslipidemia is the two facet of metabolic syndrome, which needs further
attention. Recent studies indicate triazole and indole derivatives have remarkable anti …

Abstract Seven miconazole analogs involving 1, 4, 5-tri and 1, 5-disubstituted triazole
moieties were synthesized by azide-enolate 1, 3-dipolar cycloaddition. The antifungal …