A critical analysis of the role of testosterone in erectile function: from pathophysiology to treatment—a systematic review

AM Isidori, J Buvat, G Corona, I Goldstein, EA Jannini… - European urology, 2014 - Elsevier
Context Androgen modulation of erectile function (EF) is widely accepted. However, the use
of testosterone replacement therapy (TRT) in men with erectile dysfunction (ED) has …

Endocrinologic control of men's sexual desire and arousal/erection

G Corona, AM Isidori, A Aversa… - The journal of sexual …, 2016 - academic.oup.com
Introduction Several hormones and neurotransmitters orchestrate men's sexual response,
including the appetitive (sexual desire) and consummative (arousal and penile erection) …

[HTML][HTML] Post-finasteride syndrome: a surmountable challenge for clinicians

AM Traish - Fertility and sterility, 2020 - Elsevier
Post-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested
in clinical symptoms that develop and persist in patients during and/or after discontinuing …

Persistent sexual side effects of finasteride: could they be permanent?

MS Irwig - The journal of sexual medicine, 2012 - academic.oup.com
Introduction Finasteride has been associated with sexual side effects that may persist
despite discontinuation of the medication. In a clinical series, 20% of subjects with male …

[HTML][HTML] Post-finasteride syndrome: an emerging clinical problem

S Diviccaro, RC Melcangi, S Giatti - Neurobiology of stress, 2020 - Elsevier
The presence of side effects during pharmacological treatment is unfortunately a quite
common problem. In this review, we focused our attention on adverse events related to 5 …

The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis

Z Zhou, S Song, Z Gao, J Wu, J Ma… - Clinical interventions in …, 2019 - Taylor & Francis
Aim We performed a meta-analysis to evaluate the efficacy and safety of dutasteride and
finasteride in treating men with androgenetic alopecia (AGA) during a 24-week treatment …

Sexual dysfunction in subjects treated with inhibitors of 5α‐reductase for benign prostatic hyperplasia: a comprehensive review and meta‐analysis

G Corona, G Tirabassi, D Santi, E Maseroli… - …, 2017 - Wiley Online Library
Despite their efficacy in the treatment of benign prostatic hyperplasia, the popularity of
inhibitors of 5α‐reductase (5 ARI s) is limited by their association with adverse sexual side …

Adverse effects of 5α-reductase inhibitors: what do we know, don't know, and need to know?

AM Traish, RC Melcangi, M Bortolato… - Reviews in Endocrine …, 2015 - Springer
Steroids are important physiological orchestrators of endocrine as well as peripheral and
central nervous system functions. One of the key processes for regulation of these molecules …

Challenges in testosterone measurement, data interpretation, and methodological appraisal of interventional trials

LW Trost, JP Mulhall - The journal of sexual medicine, 2016 - academic.oup.com
Introduction Male hypogonadism is a common condition, with an increasing body of
literature on diagnosis, implications, and management. Given the significant variability in …

5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety

R Dhurat, A Sharma, L Rudnicka… - Dermatologic …, 2020 - Wiley Online Library
Androgenetic alopecia (AGA) is a multifactorial disease that carries a significant
psychological burden with it. Dihydrotestosterone, the main pathogenic androgen in AGA, is …