Detergents are widely used for membrane protein solubilization, purification, and structural
analysis. Over the past two decades, much effort has been made to design novel detergents …

Membrane proteins (MPs) are usually handled in aqueous solutions as protein/detergent
complexes. Detergents, however, tend to be inactivating. This situation has prompted the …

The understanding of integral membrane protein (IMP) structure and function is hampered
by the difficulty of handling these proteins. Aqueous solubilization, necessary for many types …

The two-volume Encyclopedia of Supramolecular Chemistry offers authoritative, centralized
information on a rapidly expanding interdisciplinary field. User-friendly and high-quality …

Amphipols (APols) are short amphipathic polymers that can substitute for detergents to keep
integral membrane proteins (MPs) water soluble. In this review, we discuss their structure …

Delivering active pharmaceutical agents to disease sites using soft polymeric nanoparticles
continues to be a topical area of research. It is becoming increasingly evident that the …

When membrane proteins are removed from their natural environment, the quality of the
membrane‐solubilizing agent used is critical for preserving their native structures and …

Small angle neutron scattering (SANS) is a powerful technique for investigating association
states and conformational changes of biological macromolecules in solution. SANS is of …

Which properties of the membrane environment are essential for the folding and
oligomerization of transmembrane proteins? Because the lipids that surround membrane …

Laurylmaltose neopentylglycol (LMNG) bears two linked hydrophobic chains of equal length
and two hydrophilic maltoside groups. It arouses a strong interest in the field of membrane …