Axonal transport deficits and neurodegenerative diseases

S Millecamps, JP Julien - Nature Reviews Neuroscience, 2013 - nature.com
The intracellular transport of organelles along an axon is crucial for the maintenance and
function of a neuron. Anterograde axonal transport has a role in supplying proteins and …

Kinesin and dynein superfamily proteins and the mechanism of organelle transport

N Hirokawa - Science, 1998 - science.org
Cells transport and sort proteins and lipids, after their synthesis, to various destinations at
appropriate velocities in membranous organelles and protein complexes. Intracellular …

[图书][B] Cell movements: from molecules to motility

D Bray - 2000 - taylorfrancis.com
Cell Movements vividly describes how complex movements can arise from the properties
and behaviors of biological molecules. This second edition is updated throughout with …

Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics

N Hirokawa, Y Noda - Physiological reviews, 2008 - journals.physiology.org
Various molecular cell biology and molecular genetic approaches have indicated significant
roles for kinesin superfamily proteins (KIFs) in intracellular transport and have shown that …

Axonal mitochondrial transport and potential are correlated

KE Miller, MP Sheetz - Journal of cell science, 2004 - journals.biologists.com
Disruption of axonal transport leads to a disorganized distribution of mitochondria and other
organelles and is thought to be responsible for some types of neuronal disease. The reason …

Endoplasmic reticulum of animal cells and its organization into structural and functional domains

O Baumann, B Walz - 2001 - Elsevier
The endoplasmic reticulum (ER) in animal cells is an extensive, morphologically continuous
network of membrane tubules and flattened cisternae. The ER is a multifunctional organelle; …

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

KJ Verhey, D Meyer, R Deehan, J Blenis… - The Journal of cell …, 2001 - rupress.org
The cargo that the molecular motor kinesin moves along microtubules has been elusive. We
searched for binding partners of the COOH terminus of kinesin light chain, which contains …

Microtubule-based transport systems in neurons: the roles of kinesins and dyneins

LSB Goldstein, Z Yang - Annual review of neuroscience, 2000 - annualreviews.org
The large size and extreme polarization of neurons is crucial to their ability to communicate
at long distances and to form the complex cellular networks of the nervous system. The size …

[HTML][HTML] Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin‐based motility

G Morfini, G Szebenyi, R Elluru, N Ratner… - The EMBO …, 2002 - embopress.org
Membrane‐bounded organelles (MBOs) are delivered to different domains in neurons by
fast axonal transport. The importance of kinesin for fast antero grade transport is well …

[HTML][HTML] Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics

MA Welte, SP Gross, M Postner, SM Block… - Cell, 1998 - cell.com
In Drosophila embryos, microtubules oriented along apical–basal directions support
saltatory vesicle movement. Vesicle traffic includes lipid droplets whose distribution shifts …