Remyelination therapies, which are currently under development, have a great potential to
delay, prevent or even reverse disability in multiple sclerosis patients. Several models are …

Contactins are a group of cell adhesion molecules that are mainly expressed in the brain
and play pivotal roles in the organization of axonal domains, axonal guidance …

Background Herbicides are environmental contaminants that have gained much attention
due to the potential hazards they pose to human health. Glyphosate, the active ingredient in …

Background Mutations in the β-glucocerebrosidase (GBA1) gene do cause the lysosomal
storage Gaucher disease (GD) and are among the most frequent genetic risk factors for …

Along myelinated axons, Shaker-type potassium channels (Kv1) accumulate at high density
in the juxtaparanodal region, directly adjacent to the paranodal axon–glia junctions that …

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
diverse clinical manifestations and tissue injuries in multiple organs. However, cellular and …

In the progressive phase of multiple sclerosis (MS), the hampered differentiation capacity of
oligodendrocyte precursor cells (OPCs) eventually results in remyelination failure. We have …

Neural tissue engineering holds great promise in repairing damaged nerve tissues.
However, despite the promising results in regenerating the injured nervous system, tissue …

The cell-surface attached glycoprotein contactin 2 is ubiquitously expressed in the nervous
system and mediates homotypic cell-cell interactions to organize cell guidance …

Neonatally transplanted human glial progenitor cells (hGPCs) can myelinate the brains of
myelin-deficient shiverer mice, rescuing their phenotype and survival. Yet, it has been …