The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited
to impaired insulin signalling but also involves the complex interplay of multiple metabolic …

Studies reporting blood levels of the omega-3 polyunsaturated fatty acids, eicosapentaenoic
acid (EPA) and docosahexaenoic acid (DHA), were systematically identified in order to …

Background—Previous studies on intake of linoleic acid (LA), the predominant n-6 fatty acid,
and coronary heart disease (CHD) risk have generated inconsistent results. We performed a …

Circulating fatty acids (FA) are associated with a multitude of chronic diseases. However, a
major gap in establishing such relationships is the lack of accepted fatty acid reference …

In the last few years, the monounsaturated hexadecenoic fatty acids are being increasingly
considered as biomarkers of health with key functions in physiology and pathophysiology …

Purpose The severity of untreated or refractory diabetes mellitus has been functionally
linked to elevated concentrations of free plasma glucose, clinically defined as …

Although dietary fatty acids can modulate metabolic and immune responses, the effects of
palmitoleic acid (16: 1n‐7) remain unclear. Since this monounsaturated fatty acid is …

Ceramides and sphingolipids are a family of lipid molecules that circulate in serum and
accumulate in skeletal muscle, promoting insulin resistance. Plasma ceramide and …

Autoimmune diseases (ADs) are rapidly increasing worldwide and accumulating data
support a key role of disrupted metabolism in ADs. This study aimed to identify an improved …

Background Obesity is not a homogeneous condition across individuals since about 25–
40% of obese individuals can maintain healthy status with no apparent signs of metabolic …