Development of new potential anticancer metal complexes derived from 2-hydrazinobenzothiazole
Background: Due to the side effects of clinically approved anticancer drugs there is a great
need to explore and develop new metal-based anticancer drug molecules of high efficiency …
need to explore and develop new metal-based anticancer drug molecules of high efficiency …
Propolis-loaded nanostructured lipid carriers halt breast cancer progression through miRNA-223 related pathways: an in-vitro/in-vivo experiment
SA Shaker, SM Alshufta, MA Gowayed… - Scientific Reports, 2023 - nature.com
The most frequent malignant tumor in women is breast cancer, and its incidence has been
rising every year. Propolis has been used for its antibacterial, antifungal, and anti …
rising every year. Propolis has been used for its antibacterial, antifungal, and anti …
Nickel (II) diacetyl monoxime-2-pyridyl hydrazone complex can inhibit Ehrlich solid tumor growth in mice: A potential new antitumor drug
EA Saad, MM Hassanien, FW El-Lban - Biochemical and biophysical …, 2017 - Elsevier
The chief chemotherapeutic drug, cisplatin had common bad effects such as nephrotoxicity,
ototoxicity and bone marrow depression. This led us to develop a new potential anticancer …
ototoxicity and bone marrow depression. This led us to develop a new potential anticancer …
Regression of murine Ehrlich ascites carcinoma using synthesized cobalt complex
Cisplatin as a chief chemotherapy has nephro-toxicity and so we have tried to develop a
novel antitumor drug based on a combination of cobalt metal ion with an organic moiety. The …
novel antitumor drug based on a combination of cobalt metal ion with an organic moiety. The …
[PDF][PDF] Malondialdehyde, adiponectin, nitric oxide, C-reactive protein, tumor necrosis factor-alpha and insulin resistance relationships and inter-relationships in type 2 …
Objective: Great interest is directed to inflammation and oxidative stress involvement in type
2 diabetes pathogenesis. Many researchers suggest they play roles but exactly how is still …
2 diabetes pathogenesis. Many researchers suggest they play roles but exactly how is still …
Frankincense administration antagonizes adenine-induced chronic renal failure in rats
Background: Chronic renal failure (CRF) treatment through kidney transplantation or dialysis
is restricted because of economic and medical resources deficiency. Thus, demand for using …
is restricted because of economic and medical resources deficiency. Thus, demand for using …
Hepato-toxic risk of gum arabic during adenine-induced renal toxicity prevention
Objective: Lately, gum arabic (GA) is traditionally used in Middle East countries to ameliorate
renal function of patients with chronic renal failure (CRF). This action is controversial and it is …
renal function of patients with chronic renal failure (CRF). This action is controversial and it is …
A newly synthesized derivative and a natural parent molecule: Which would be more beneficial as a future antitumor candidate? Docking and in vivo study
EA Saad, F Zahran, FZ El-Ablack… - Applied Biochemistry and …, 2022 - Springer
Seeking for new effectual anticancer drugs is of great importance. In this study, a newly
synthesized and well-characterized chromene derivative (ethyl 2-amino-4-phenyl-4H-benzo …
synthesized and well-characterized chromene derivative (ethyl 2-amino-4-phenyl-4H-benzo …
Loading of some quinoxaline derivatives in poly (l-lactic) acid/Pluronic® F-127 nanofibers enhances their anticancer efficiency and induces a p53 and p21 apoptotic …
The objective of this study was to evaluate the anticancer activity on cancer cell models of a
drug delivery system consisting of poly (l-lactic) acid/Pluronic® F-127 (PLLA/PF127) loaded …
drug delivery system consisting of poly (l-lactic) acid/Pluronic® F-127 (PLLA/PF127) loaded …
The new iron (III) 3‐oxo‐N‐(pyridin‐2‐yl) butanamide complex promotes Ehrlich solid tumor regression in mice via induction of apoptosis
Currently used chemotherapeutic drugs had serious adverse effects eg myelo‐suppression,
anemia and nephrotoxicity. Thus, developing new alternatives is of great importance. We …
anemia and nephrotoxicity. Thus, developing new alternatives is of great importance. We …