Drug resistance is estimated to affect about a third of individuals with epilepsy, but its
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …

More than 150 years after bromide was introduced as the first antiepileptic drug, adverse
effects remain a leading cause of treatment failure and a major determinant of impaired …

Many recent epidemiological studies have found the prevalence of depression and anxiety
to be higher in people with epilepsy (PWE) than in people without epilepsy. Furthermore …

Objective Generalized anxiety disorder (GAD) in people with epilepsy (PWE) is
underdiagnosed and undertreated. The GAD-7 is a screening questionnaire to detect GAD …

Purpose To understand the currently available post-marketing real-world evidence of the
incidences of and discontinuations due to the BAEs of irritability, anger, and aggression in …

Accurate identification of seizure activity, both clinical and subclinical, has important
implications in the management of epilepsy. Accurate recognition of seizure activity is …

Objective Seizure unpredictability is rated as one of the most challenging aspects of living
with epilepsy. Seizure likelihood can be influenced by a range of environmental and …

Introduction Our objective was to provide expert consensus recommendations to improve
treatment tolerability through dose adjustments of concomitant antiseizure medications …

Abstract The Generalized Anxiety Disorder-7 (GAD-7) is a valuable instrument to screen for
anxiety in primary care patients. However, it has not been validated in people with epilepsy …

Objective To evaluate whether vagus nerve stimulation (VNS) as adjunct to best medical
practice (VNS+ BMP) is superior to BMP alone in improving long‐term health‐related quality …