Architecture of the dynamic fungal cell wall

NAR Gow, MD Lenardon - Nature Reviews Microbiology, 2023 - nature.com
The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

Solid-state NMR investigations of extracellular matrixes and cell walls of algae, bacteria, fungi, and plants

N Ghassemi, A Poulhazan, F Deligey… - Chemical …, 2021 - ACS Publications
Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR

A Chakraborty, LD Fernando, W Fang… - Nature …, 2021 - nature.com
Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall,
but the supramolecular architecture of this carbohydrate-rich composite remains …

Chitosan-based biomaterials: insights into chemistry, properties, devices, and their biomedical applications

S Petroni, I Tagliaro, C Antonini, M D'Arienzo, SF Orsini… - Marine drugs, 2023 - mdpi.com
Chitosan is a marine-origin polysaccharide obtained from the deacetylation of chitin, the
main component of crustaceans' exoskeleton, and the second most abundant in nature …

Identification and quantification of glycans in whole cells: architecture of microalgal polysaccharides described by solid-state nuclear magnetic resonance

A Poulhazan, MC Dickwella Widanage… - Journal of the …, 2021 - ACS Publications
Microalgae are photosynthetic organisms widely distributed in nature and serve as a
sustainable source of bioproducts. Their carbohydrate components are also promising …

Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition

G Lamon, A Lends, I Valsecchi… - Proceedings of the …, 2023 - National Acad Sciences
While establishing an invasive infection, the dormant conidia of Aspergillus fumigatus transit
through swollen and germinating stages, to form hyphae. During this morphotype transition …

[HTML][HTML] Fungal textile alternatives from bread waste with leather-like properties

ERKB Wijayarathna, G Mohammadkhani… - Resources …, 2022 - Elsevier
Food waste and fashion pollution are two of the most prominent global environmental
issues. To alleviate the problems associated with food waste, while simultaneously …

Insect-derived chitin and chitosan: A still unexploited resource for the edible insect sector

K Rehman, C Hollah, K Wiesotzki, V Heinz, K Aganovic… - Sustainability, 2023 - mdpi.com
Chitin and chitosan are biopolymers that are frequently found in nature and have a broad
range of applications in the food, biomedical and industrial sectors, due to their high …

Adaptative survival of Aspergillus fumigatus to echinocandins arises from cell wall remodeling beyond β− 1, 3-glucan synthesis inhibition

MC Dickwella Widanage, I Gautam, D Sarkar… - Nature …, 2024 - nature.com
Antifungal echinocandins inhibit the biosynthesis of β− 1, 3-glucan, a major and essential
polysaccharide component of the fungal cell wall. However, the efficacy of echinocandins …

Molecular architecture of chitin and chitosan-dominated cell walls in zygomycetous fungal pathogens by solid-state NMR

Q Cheng, MC Dickwella Widanage, JR Yarava… - Nature …, 2024 - nature.com
Zygomycetous fungal infections pose an emerging medical threat among individuals with
compromised immunity and metabolic abnormalities. Our pathophysiological understanding …