Invasiveness in pituitary adenomas has been defined and investigated from multiple
perspectives, with varying results when its predictive value is considered. A systematic …

The tumour microenvironment (TME) includes a variety of non-neoplastic cells and non-
cellular elements such as cytokines, growth factors and enzymes surrounding tumour cells …

Non-tumoural cells within the tumour microenvironment (TME) influence tumour
proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary …

Understanding the physiology and pathology of an organ composed of a variety of cell
populations depends critically on genome-wide information on each cell type. Here, we …

OBJECTIVE The medial wall of the cavernous sinus (CS) is often invaded by pituitary
adenomas. Surgical mobilization and/or removal of the medial wall remains a challenge …

Background Transsphenoidal surgery is the first-choice treatment for acromegaly.
Postoperative remission is an important predictor of outcome. Various factors have been …

Propranolol, a lipophilic nonselective β-blocker, has recently been reported to be the
treatment of choice for select types of infantile hemangiomas (IHs). Atenolol is a hydrophilic …

The extracellular matrix is important for tumor invasion and metastasis. Normal function of
the extracellular matrix depends on the balance between matrix metalloproteinases (MMPs) …

The medial wall of the cavernous sinus (CS) has a significant role in evaluation and
treatment of pituitary adenomas. This study was conducted to clarify the fine architecture of …

Background Cathepsin K (CTSK) is a protease that degrades type I collagen and
extracellular matrix, thereby contributing to bone resorption and tumor invasion. Some …