PARALOGOUS HOX GENES: Function and Regulation

M Maconochie, S Nonchev, A Morrison… - Annual review of …, 1996 - annualreviews.org
▪ Abstract The Hox homeobox gene family plays a pivotal role in regulating patterning and
axial morphogenesis in vertebrates. Molecular characterization of the four Hox clusters has …

The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution

D Duboule - BioEssays, 1992 - Wiley Online Library
The potential of the vertebrate limb as a model system to study developmental mechanisms
is particularly well illustrated by the analysis of the Hox gene network. These genes are …

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

P Dollé, JC Izpisúa-Belmonte, H Falkenstein… - Nature, 1989 - nature.com
The homoeobox-containing genes of the Hox-5 complex are expressed in different but
overlapping domains in limbs during murine development. The more 5′ the position of …

Murine developmental control genes

M Kessel, P Gruss - Science, 1990 - science.org
Various strategies have been used to isolate genes that participate in the regulation of
mouse development. Gene families that have been identified on the basis of their homology …

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

JC Izpisúa‐Belmonte, H Falkenstein, P Dollé… - The EMBO …, 1991 - embopress.org
The cloning, characterization and developmental expression patterns of two novel murine
Hox genes, Hox‐4.6 and Hox‐4.7, are reported. Structural data allow us to classify the four …

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

R Ramfrez-Solis, H Zheng, J Whiting, R Krumlauf… - Cell, 1993 - cell.com
Summary Two Hoxb4 (Hox-2.6) mutations were introduced into the mouse germline. The
overt phenotype caused by one of the mutations was assayed on two dlfferent genetic …

A homeotic gene cluster patterns the anteroposterior body axis of C. elegans

BB Wang, MM Müller-Immergluck, J Austin… - Cell, 1993 - cell.com
Summary in Insects and vertebrates, clusters of AnfennapedCa class homeobox (HOM-C)
genes specify anteroposterlor body pattern. The nematode C. eiegana also contains a small …

The zinc finger gene Krox20 regulates HoxB2 (Hox2. 8) during hindbrain segmentation

MH Sham, C Vesque, S Nonchev, H Marshall, M Frain… - Cell, 1993 - cell.com
The zinc finger gene Krox20 and many Hox homeobox genes are expressed in segment-
rest&ted domains in the hindbrain. The restricted expression patterns appear before …

Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach

JP Tissier-Seta, ML Mucchielli, M Mark… - Mechanisms of …, 1995 - Elsevier
In the process of cloning murine proteins capable of binding to a regulatory module of the
Ncam promoter, we isolated a novel homeobox gene, Barx1, the first vertebrate member of …

HOM/HOX homeobox genes are present in hydra (Chlorohydra viridissima) and are differentially expressed during regeneration.

M Schummer, I Scheurlen, C Schaller, B Galliot - The EMBO journal, 1992 - embopress.org
Hydra, a diblastic animal consisting of two cell layers, ectoderm and endoderm, is one of the
most ancient animals displaying an anteroposterior axis with a head and a foot developing …