The occurrence of cancer entails a series of genetic mutations that favor uncontrollable
tumor growth. It is believed that various factors collectively contribute to cancer, and there is …

The critical role of dysregulated epigenetic pathways in cancer genesis, development, and
therapy has typically been established as a result of scientific and technical innovations in …

Neural crest cells (NCCs) are a dynamic, multipotent, vertebrate-specific population of
embryonic stem cells. These ectodermally-derived cells contribute to diverse tissue types in …

Iron plays an important role in mammalian physiological processes. It is a critical component
for the function of many proteins, including enzymes that require heme and iron-sulfur …

De novo variants are a leading cause of neurodevelopmental disorders (NDDs), but
because every monogenic NDD is different and usually extremely rare, it remains a major …

Chronic inflammation (CI) is a primary contributing factor involved in multiple diseases like
cancer, stroke, diabetes, Alzheimer's disease, allergy, asthma, autoimmune diseases …

Fighting cancer is one of the major challenges of the 21st century. Among recently proposed
treatments, molecular-targeted therapies are attracting particular attention. The potential …

Pulmonary arterial hypertension (PAH) is a disease that progress over time and is defined
as an increase in pulmonary arterial pressure and pulmonary vascular resistance that …

Cancer is a major cause of death worldwide. Epigenetic changes in response to external
(diet, sports activities, etc.) and internal events are increasingly implicated in tumor initiation …

The negative regulation of antiviral immune responses is essential for the host to maintain
homeostasis. Jumonji domain-containing protein 6 (JMJD6) was previously identified with a …