Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

[HTML][HTML] The effects of baicalin and baicalein on cerebral ischemia: a review

W Liang, X Huang, W Chen - Aging and disease, 2017 - ncbi.nlm.nih.gov
Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease.
Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin …

[HTML][HTML] The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro

J Song, L Zhang, Y Xu, D Yang, S Yang… - Biochemical …, 2021 - Elsevier
Baicalein is the main active compound of Scutellaria baicalensis Georgi, a medicinal herb
with multiple pharmacological activities, including the broad anti-virus effects. In this paper …

Простые лекарственные средства

ИД Кароматов - 2012 - elibrary.ru
Монография попытка автора воссоединить воедино данные народной, традиционной
и научной медицины по применению лекарственных средств натурального …

[HTML][HTML] Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage

S Yang, H Wang, Y Yang, R Wang, Y Wang… - Biomedicine & …, 2019 - Elsevier
Ischemic stroke is a cerebrovascular disease with high morbidity, high mortality, and high
disability, representing a serious threat to human life and health. Clinically, the extensive …

Molecular mechanisms of vascular dementia: what can be learned from animal models of chronic cerebral hypoperfusion?

SQ Du, XR Wang, LY Xiao, JF Tu, W Zhu, T He… - Molecular …, 2017 - Springer
Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive
decline, attributable to cerebrovascular factors. Numerous studies have demonstrated that …

Baicalein as a potent neuroprotective agent: A review

K Sowndhararajan, P Deepa, M Kim, SJ Park… - Biomedicine & …, 2017 - Elsevier
In recent times, neurodegenerative diseases are the most challenging global health
problems. Neuronal cell death or damage is a key factor for many neurodegenerative …

The vitamin nicotinamide: translating nutrition into clinical care

K Maiese, ZZ Chong, J Hou, YC Shang - Molecules, 2009 - mdpi.com
Nicotinamide, the amide form of vitamin B3 (niacin), is changed to its mononucleotide
compound with the enzyme nicotinic acide/nicotinamide adenylyl-transferase, and …

The effects of baicalein and baicalin on mitochondrial function and dynamics: A review

MR De Oliveira, SF Nabavi, S Habtemariam… - Pharmacological …, 2015 - Elsevier
Mitochondria play an essential role in cell survival by providing energy, calcium buffering,
and regulating apoptosis. A growing body of evidence shows that mitochondrial dysfunction …

Baicalein loaded in tocol nanostructured lipid carriers (tocol NLCs) for enhanced stability and brain targeting

MJ Tsai, PC Wu, YB Huang, JS Chang, CL Lin… - International journal of …, 2012 - Elsevier
The objective of the present work was to investigate the specific brain targeting of baicalein
by intravenous injection after incorporation into nanostructured lipid carriers (NLCs). The …