W Liang, X Huang, W Chen - Aging and disease, 2017 - ncbi.nlm.nih.gov
Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease. Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin …
J Song, L Zhang, Y Xu, D Yang, S Yang… - Biochemical …, 2021 - Elsevier
Baicalein is the main active compound of Scutellaria baicalensis Georgi, a medicinal herb with multiple pharmacological activities, including the broad anti-virus effects. In this paper …
S Yang, H Wang, Y Yang, R Wang, Y Wang… - Biomedicine & …, 2019 - Elsevier
Ischemic stroke is a cerebrovascular disease with high morbidity, high mortality, and high disability, representing a serious threat to human life and health. Clinically, the extensive …
SQ Du, XR Wang, LY Xiao, JF Tu, W Zhu, T He… - Molecular …, 2017 - Springer
Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive decline, attributable to cerebrovascular factors. Numerous studies have demonstrated that …
In recent times, neurodegenerative diseases are the most challenging global health problems. Neuronal cell death or damage is a key factor for many neurodegenerative …
Nicotinamide, the amide form of vitamin B3 (niacin), is changed to its mononucleotide compound with the enzyme nicotinic acide/nicotinamide adenylyl-transferase, and …
Mitochondria play an essential role in cell survival by providing energy, calcium buffering, and regulating apoptosis. A growing body of evidence shows that mitochondrial dysfunction …
MJ Tsai, PC Wu, YB Huang, JS Chang, CL Lin… - International journal of …, 2012 - Elsevier
The objective of the present work was to investigate the specific brain targeting of baicalein by intravenous injection after incorporation into nanostructured lipid carriers (NLCs). The …