MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that play important
roles in the development and functions of the brain. Extensive studies have revealed critical …

The post-transcriptional regulator molecules, microRNAs, have emerged as important
biomarkers and modulators of numerous pathophysiological processes including …

Objectives: This review presents and discusses basic science findings and scientific
evidence generated within the last 2 decades in the field of acute postoperative pain …

Abstract Background Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been
implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

Chronic pain arising from peripheral inflammation and tissue or nerve injury is a common
clinical symptom. Although intensive research on the neurobiological mechanisms of …

Scratching and scratch-induced injuries, including neuroanatomical alterations, are key
characteristics of chronic pruritus entities of different origins. The aim of this study was to link …

Chronic pain is a major public health issue with an incidence of 20–25% worldwide that can
take different forms like neuropathic, cancer-related or inflammatory pain. Chronic pain often …

Abstract The methyltransferase-like 3 (Mettl3) is a key component of the large N6-adenosine-
methyltransferase complex in mammalian responsible for RNA N6-methyladenosine (m6A) …

Chronic pain remains an unresolved problem. Current treatments have limited efficacy.
Thus, novel therapeutic targets are urgently required for the development of more effective …