Disorders of consciousness after acquired brain injury: the state of the science

JT Giacino, JJ Fins, S Laureys, ND Schiff - Nature Reviews Neurology, 2014 - nature.com
The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

Resting brain activity in disorders of consciousness: a systematic review and meta-analysis

Y Hannawi, MA Lindquist, BS Caffo, HI Sair… - Neurology, 2015 - AAN Enterprises
Objective: To quantitatively synthesize results from neuroimaging studies that evaluated
patterns of resting functional activity in patients with disorders of consciousness (DOC) …

Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study

C Di Perri, MA Bahri, E Amico, A Thibaut… - The Lancet …, 2016 - thelancet.com
Background Between pathologically impaired consciousness and normal consciousness
exists a scarcely researched transition zone, referred to as emergence from minimally …

Intrinsic functional connectivity patterns predict consciousness level and recovery outcome in acquired brain injury

X Wu, Q Zou, J Hu, W Tang, Y Mao, L Gao… - Journal of …, 2015 - Soc Neuroscience
For accurate diagnosis and prognostic prediction of acquired brain injury (ABI), it is crucial to
understand the neurobiological mechanisms underlying loss of consciousness. However …

The rich get richer: brain injury elicits hyperconnectivity in core subnetworks

FG Hillary, SM Rajtmajer, CA Roman, JD Medaglia… - PloS one, 2014 - journals.plos.org
There remains much unknown about how large-scale neural networks accommodate
neurological disruption, such as moderate and severe traumatic brain injury (TBI). A primary …

Recent advances in disorders of consciousness: focus on the diagnosis

O Gosseries, ND Zasler, S Laureys - Brain injury, 2014 - Taylor & Francis
Background: Over the last two decades, there has been a considerable increase in
knowledge of brain function in patients with disorders of consciousness following a coma …

How are different neural networks related to consciousness?

P Qin, X Wu, Z Huang, NW Duncan, W Tang… - Annals of …, 2015 - Wiley Online Library
Objective We aimed to investigate the roles of different resting‐state networks in predicting
both the actual level of consciousness and its recovery in brain injury patients. Methods We …

Whole‐brain analyses indicate the impairment of posterior integration and thalamo‐frontotemporal broadcasting in disorders of consciousness

R Panda, A López‐González, M Gilson… - Human Brain …, 2023 - Wiley Online Library
The study of the brain's dynamical activity is opening a window to help the clinical
assessment of patients with disorders of consciousness. For example, glucose uptake and …

Functional networks in disorders of consciousness

YG Bodien, C Chatelle, BL Edlow - Seminars in neurology, 2017 - thieme-connect.com
Severe brain injury may cause disruption of neural networks that sustain arousal and
awareness, the two essential components of consciousness. Despite the potentially …

Functional neuroanatomy of disorders of consciousness

C Di Perri, J Stender, S Laureys, O Gosseries - Epilepsy & Behavior, 2014 - Elsevier
Our understanding of the mechanisms of loss and recovery of consciousness, following
severe brain injury or during anesthesia, is changing rapidly. Recent neuroimaging studies …