Patient-Centric Knowledge Graphs: A Survey of Current Methods, Challenges, and Applications

HSA Khatib, S Neupane, HK Manchukonda… - arXiv preprint arXiv …, 2024 - arxiv.org
Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that
focuses on individualized patient care by mapping the patient's health information in a …

[HTML][HTML] RDKG-115: assisting drug repurposing and discovery for rare diseases by trimodal knowledge graph embedding

C Zhu, X Xia, N Li, F Zhong, Z Yang, L Liu - Computers in Biology and …, 2023 - Elsevier
Rare diseases (RDs) may affect individuals in small numbers, but they have a significant
impact on a global scale. Accurate diagnosis of RDs is challenging, and there is a severe …

Knowledge graphs in psychiatric research: Potential applications and future perspectives

S Freidel, E Schwarz - Acta Psychiatrica Scandinavica, 2024 - Wiley Online Library
Abstract Background Knowledge graphs (KGs) remain an underutilized tool in the field of
psychiatric research. In the broader biomedical field KGs are already a significant tool …

Integrative rare disease biomedical profile based network supporting drug repurposing or repositioning, a case study of glioblastoma

E McGowan, J Sanjak, EA Mathé, Q Zhu - Orphanet Journal of Rare …, 2023 - Springer
Background Glioblastoma (GBM) is the most aggressive and common malignant primary
brain tumor; however, treatment remains a significant challenge. This study aims to identify …

[HTML][HTML] Integrative Rare Disease Biomedical Profile based Network Supporting Drug Repurposing, a case study of Glioblastoma

E McGowan, J Sanjak, EA Mathé, Q Zhu - Research Square, 2023 - ncbi.nlm.nih.gov
Background Glioblastoma (GBM) is the most aggressive and common malignant primary
brain tumor; however, treatment remains a significant challenge. This study aims to identify …

[HTML][HTML] The division of rare diseases research innovation at the national center for advancing translational sciences, NIH: mission, history, and current research …

PJ Brooks, AC Grady, S Groft, L Ho… - Rare Disease and …, 2024 - oaepublish.com
The mission of the NCATS Division of Rare Diseases Research Innovation (DRDRI),
formerly known as the Office of Rare Diseases Research, is to advance rare diseases …