Curcumin—from molecule to biological function

T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …

Age‐related macular degeneration: new paradigms for treatment and management of AMD

LF Hernández-Zimbrón… - Oxidative medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …

Microglia as a source and target of cytokines

UK Hanisch - Glia, 2002 - Wiley Online Library
Cytokines constitute a significant portion of the immuno‐and neuromodulatory messengers
that can be released by activated microglia. By virtue of potent effects on resident and …

[HTML][HTML] Glia and alpha-synuclein in neurodegeneration: A complex interaction

D Brück, GK Wenning, N Stefanova, L Fellner - Neurobiology of disease, 2016 - Elsevier
Abstract α-Synucleinopathies (ASP) comprise adult-onset, progressive neurodegenerative
disorders such as Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple …

Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina

M Wang, W Ma, L Zhao, RN Fariss… - Journal of …, 2011 - Springer
Purpose Microglia and Müller cells are prominent participants in retinal responses to injury
and disease that shape eventual tissue adaptation or damage. This investigation examined …

Targeting astrocytes in CNS injury and disease: A translational research approach

AR Filous, J Silver - Progress in neurobiology, 2016 - Elsevier
Astrocytes are a major constituent of the central nervous system. These glia play a major
role in regulating blood-brain barrier function, the formation and maintenance of synapses …

Central neuron–glial and glial–glial interactions following axon injury

H Aldskogius, EN Kozlova - Progress in neurobiology, 1998 - Elsevier
Axon injury rapidly activates microglial and astroglial cells close to the axotomized neurons.
Following motor axon injury, astrocytes upregulate within hour (s) the gap junction protein …

The therapeutic role of interleukin-10 after spinal cord injury

CD Thompson, JC Zurko, BF Hanna… - Journal of …, 2013 - liebertpub.com
Spinal cord injury (SCI) is a devastating condition affecting 270,000 people in the United
States. A potential treatment for decreasing the secondary inflammation, excitotoxic damage …

Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study

H Wilson, G Dervenoulas, G Pagano, RJ Tyacke… - Brain, 2019 - academic.oup.com
Astroglia are multifunctional cells that regulate neuroinflammation and maintain
homeostasis within the brain. Astroglial α-synuclein-positive cytoplasmic accumulations …

The complement system: a powerful modulator and effector of astrocyte function in the healthy and diseased central nervous system

M Pekna, M Pekny - Cells, 2021 - mdpi.com
The complement system, an effector arm of the innate immune system that plays a critical
role in tissue inflammation, the elimination of pathogens and the clearance of dead cells and …