This meeting was organized by The Transplantation Society with the assistance of an
unconditional education grant from CSL Behring. CSL Behring had no involvement in the …

Abstract Although anti–HLA (Human Leukocyte Antigen) donor-specific antibodies (DSAs)
are commonly measured in clinical practice and their relationship with transplant outcome is …

The use of routine monitoring of donor-derived cell-free DNA (dd-cfDNA) after kidney
transplant may allow clinicians to identify subclinical allograft injury and intervene prior to …

In organ transplantation, infection and rejection are major causes of graft loss. They are
linked by the net state of immunosuppression. To diagnose and treat these conditions …

Solid organ transplantation is a curative therapy for hundreds of thousands of patients with
end-stage organ failure. However, long-term outcomes have not improved, and nearly half of …

Despite the success of desensitization protocols, antibody-mediated rejection (AMR)
remains a significant contributor to renal allograft failure in patients with donor-specific …

Advances in immunosuppressive therapy have drastically improved acute rejection rates in
kidney transplant recipients over the past five decades. Nevertheless, it should remain high …

Background Correlation between antibody-mediated rejection (ABMR) and circulating HLA
donor-specific antibodies (HLA-DSA) is strong but imperfect in kidney transplant (KT) …

Immunoglobulin glycosylation is a pivotal mechanism that drives the diversification of
antibody functions. The composition of the IgG glycome is influenced by environmental …

Extracellular vesicles (EV) are emerging mediators in several diseases. However, their role
in the pathophysiology of antibody-mediated allograft rejection (AMR) has been poorly …