Occupational exposure is an important, global cause of respiratory disease. Unlike many
other non-communicable lung diseases, the proximal causes of many occupational lung …

Diacetyl, noted for its appealing butter‐like aroma, is present naturally in many foods, and
humans have been exposed to it since the beginning of civilization. The advent of …

Flavorings-related lung disease is a potentially disabling and sometimes fatal lung disease
of workers making or using flavorings. First identified almost 20 years ago in microwave …

Use of the e-liquid flavourings diacetyl and acetyl propionyl has raised concerns that they
might cause respiratory diseases amongst vapers. Product surveys show that these …

Obliterative bronchiolitis (OB)(formerly termed bronchiolitis obliterans), is a rare fibrotic
disorder involving terminal and respiratory bronchioles. The term constrictive bronchiolitis is …

Clinicians need a high index of suspicion for constrictive bronchiolitis in young patients with
rapidly progressing exertional dyspnea, regardless of spirometric and radiologic findings …

Diacetyl substitutes cause similar peri-bronchiolar fibrotic lesions in animal studies. Their
use may continue to place workers at risk for flavoring-induced lung disease, which may …

For half of the 30-odd years that diacetyl-exposed workers have developed disabling lung
disease, obliterative bronchiolitis was unrecognized as an occupational risk. Delays in its …

Abstract The European Union Tobacco Products Directive (EU TPD) mandates enhanced
reporting obligations for tobacco manufacturers regarding 15 priority additives. Within the …

Objectives To better understand respiratory symptoms and lung function in flavouring
manufacturing workers. Methods We offered a questionnaire and lung function testing to the …