Biginelli reaction involves acid-catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2 (1 H)-
ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active …

Efficient catalysis is essential from a green chemistry perspective. Porous organic polymers
(POPs) have recently emerged as highly effective materials for catalytic applications. POPs …

Antimicrobial resistance was one of the top priorities for global public health before the start
of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical …

In the chemistry world, the year 1891 was considered as milestone year for the discovery of
new type of heterocyclic compounds by Pietro Biginelli. The Biginelli protocol provides 3, 4 …

The current manuscript describes the role and importance of catalysis and solvent effects for
the Biginelli multicomponent reaction. The overwhelming number of new catalysts and …

Clays and modified or supported clays have become some of the widely used catalysts for a
variety of organic reactions, due to their easy structural modifications and activation, low …

This paper describes the use of common Lewis acids supported in imidazolium-based ionic
liquids as the catalysts to promote the Biginelli reaction. The ionic liquid effect and the …

Bronsted and Lewis acid catalysts with ionic tags under homogeneous and heterogeneous
conditions have been tested to perform the Biginelli synthesis of 3, 4-dihydropyrimidin-2 (1 …

Perlite sulfonic acid (Perlite-SO 3 H (PeSA)) has been synthesized by grafting the sulfonic
groups on the perlite surface as naturally and cheap support to produce novel …

The use of the renewable platform molecule 5-hydroxymethylfurfural (HMF) in the multi-
component Biginelli reaction has been investigated. Multicomponent reactions (MCR) using …