Drug transporter proteins are critical to the distribution of a wide range of endogenous
compounds and xenobiotics such as hormones, bile acids, peptides, lipids, sugars, and …

Abstract Glycine transporters (GlyTs) are Na+/Cl−-dependent neurotransmitter transporters,
responsible for l-glycine uptake into the central nervous system. GlyTs are members of the …

Modulation of neurotransmission by the monoamines dopamine (DA), norepinephrine (NE),
and serotonin (5-HT) is critical for normal nervous system function. Precise temporal and …

Monoamine transporters function in neuronal membranes to control extracellular
concentrations of their substrates. Cell-surface expression of transporters is regulated by …

Introduction: Melanoma differentiation-associated gene–9 (MDA-9)/Syntenin has become an
increasingly popular focus for investigation in numerous cancertypes. Originally implicated …

Flotillins were proposed to mediate clathrin‐independent endocytosis, and recently, flotillin‐
1 was implicated in the protein kinase C (PKC)‐triggered endocytosis of the dopamine …

The main glutamate transporter in the brain, GLT‐1, mediates glutamatergic
neurotransmission in both physiological and pathological conditions. GLT‐1 activity is …

The neuronal glycine transporter GlyT2 plays a fundamental role in the glycinergic
neurotransmission by recycling the neurotransmitter to the presynaptic terminal. GlyT2 is the …

We investigated the genome of a 5-year-old male who presented with global developmental
delay (motor, cognitive, and speech), hypotonia, possibly ataxia, and cerebellar hypoplasia …

To enable transmission of information in the brain, synaptic vesicles fuse to presynaptic
membranes, liberating their content and exposing transiently a myriad of vesicular …