The role of the D3 dopamine receptor and its partial agonist cariprazine in patients with schizophrenia and substance use disorder

H Grunze - Expert Opinion on Pharmacotherapy, 2023 - Taylor & Francis
Introduction Comorbidity of substance use disorder (SUD) with schizophrenia, referred to as
dual disorder (DD), significantly increases morbidity and mortality compared to …

Rethinking clozapine: lights and shadows of a revolutionary drug

L Dell'Osso, C Bonelli, B Nardi, F Giovannoni… - Brain Sciences, 2024 - mdpi.com
The current literature globally highlights the efficacy of Clozapine in several psychiatric
disorders all over the world, with an FDA indication for reducing the risk of repeated suicidal …

Association of clozapine treatment and rate of methamphetamine or amphetamine relapses and abstinence among individuals with concurrent schizophrenia …

R Rafizadeh, L Frankow, H Mahmood… - Journal of …, 2023 - journals.sagepub.com
Background: Preliminary evidence suggest clozapine is associated with more favorable
impact on concurrent substance use disorder related outcomes in patients with concurrent …

[HTML][HTML] Navigating the Complex Intersection of Substance Use and Psychiatric Disorders: A Comprehensive Review

A Bahji - Journal of Clinical Medicine, 2024 - mdpi.com
The co-occurrence of substance use disorders (SUDs) and psychiatric conditions, often
referred to as comorbidity or concurrent disorders, presents intricate challenges in both …

Investigating the effectiveness of brexpiprazole in subjects with schizophrenia spectrum illness and co-occurring substance use disorder: a prospective, multicentric …

S Chiappini, C Cavallotto, A Mosca, F Di Carlo, T Piro… - Pharmaceuticals, 2024 - mdpi.com
Background: Dual disorders (DDs) involve the coexistence of a substance use disorder
(SUD) with another mental illness, often from the psychotic and affective categories. They …

[HTML][HTML] The patient journey project in Italian mental health services: results from a co-designed survey on clinical interventions and current barriers to improve the …

A Vita, S Barlati, M Porcellana, E Sala, J Lisoni… - Frontiers in …, 2024 - frontiersin.org
Introduction The Patient Journey Project aimed to analyze the scenario among Italian Mental
Health Services (MHS) to understand the clinical interventions that are properly …

Overcoming the barriers to identifying and managing treatment-resistant schizophrenia and to improving access to clozapine: A narrative review and recommendation …

O Agid, B Crespo-Facorro, A de Bartolomeis… - European …, 2024 - Elsevier
Clozapine is the only approved antipsychotic for treatment-resistant schizophrenia (TRS).
Although a large body of evidence supports its efficacy and favorable risk-benefit ratio in …

[HTML][HTML] Examining Lurasidone Efficacy in Patients with Schizophrenia Spectrum Illness and Concurrent Alcohol and Substance Use Disorder: A Prospective …

C Cavallotto, S Chiappini, A Mosca, G d'Andrea… - Journal of Clinical …, 2024 - mdpi.com
Background: Dual disorders (DD) entail the coexistence of a substance use disorder (SUD)
and another mental health condition, often within psychotic and affective disorders. This …

Antipsychotic Use and Psychiatric Hospitalization in First-Episode Non-affective Psychosis and Cannabis Use Disorder: A Swedish Nationwide Cohort Study

A Denissoff, H Taipale, J Tiihonen… - Schizophrenia …, 2024 - academic.oup.com
Abstract Background and Hypothesis There is a paucity of research on treatment outcomes
of patients with psychosis and cannabis use disorder (CUD). We aimed to compare the …

Clinical quandaries in psychotic disorders: the road is long, with many a winding turn

S Jauhar, RA McCutcheon - Journal of Psychopharmacology, 2023 - journals.sagepub.com
The author (s) declared the following potential conflicts of interest with respect to the
research, authorship, and/or publication of this article: SJ has received honoraria for non …