Caveolin-1 (Cav-1) is an integral scaffolding membrane protein found in most cell types. Cav-
1 has been found to contribute significantly to ocular function, with mutations of Cav-1 being …

Medical stents are vital for treating vascular complications and restoring blood flow in
millions of patients. Despite its widespread effectiveness, restenosis, driven by the complex …

Purpose: The purpose of this study was to identify a precise location of deep capillary plexus
(DCP) injury in acute macular neuroretinopathy (AMN) lesions using multimodal imaging …

Regeneration of orofacial tissues is hampered by the lack of adequate vascular supply.
Implantation of in vitro engineered, prevascularized constructs has emerged as a strategy to …

Sprouting angiogenesis is an essential vascularization mechanism consisting of sprouting
and remodelling. The remodelling phase is driven by rearrangements of endothelial cells …

The etiology of spaceflight-associated neuro-ocular syndrome (SANS) remains unclear.
Recent murine studies indicate there may be a link between the space environment and …

Various biological processes such as transport of oxygen and nutrients, thrombus formation,
vascular angiogenesis and remodeling are related to cellular/subcellular level biological …

Glaucoma is a neurodegenerative disease, which results in characteristic visual field
defects. Intraocular pressure (IOP) remains the main risk factor for this leading cause of …

Engineering tissues with an embedded vasculature of well-controlled topology remains one
of the basic problems in biofabrication. Still, little is known about the evolution of topological …

Vascular remodeling is critical for tumor progression and significantly affects anti-vascular
therapies. However, the interplay between blood flow and vascular endothelial growth factor …