Background Pain is a vital sense that indicates the risk of injury at a particular body part.
Successful control of pain is the principal aspect in medical treatment. In recent years, the …

Chemotherapy-induced neuropathic pain (CINP) is among the most common clinical
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …

Background In the extracellular environment, lysophosphatidic acid (LPA) species are
generated via autotaxin (ATX)-mediated hydrolysis of lysophospholipid precursors …

Chemotherapy drugs such as vincristine (Vin) could cause neuropathic pain. However, it is
still lack of ideal therapeutic strategy to treat it. Mitochondrial dysfunction has been involved …

Inflammatory and neuropathic pain is initiated by tissue inflammation and nerve injury,
respectively. Both are characterized by increased activity in the peripheral and central …

The proximity and association of cerebrospinal fluid (CSF) and the intrathecal (IT) space with
deep targets in the central nervous system (CNS) parenchyma makes IT injection an …

Osteoarthritis (OA) is the most common joint disorder that has had an increasing prevalence
due to the aging of the population. Recent studies have concluded that OA progression is …

Nanoparticles (NPs) that target multiple transport mechanisms facilitate targeted delivery of
active therapeutic agents to the central nervous system (CNS) and improve therapeutic …

Recent clinical and pathological evidence have implicated the gut microbiota as a nexus for
modulating the homeostasis of the human body, impacting conditions from cancer and …

Abstract Background Non‐coding RNAs (ncRNAs) are involved in neuropathic pain
development. Herein, we systematically searched for neuropathic pain‐related ncRNAs …