Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Recent advances in mucoadhesive interface materials, mucoadhesion characterization, and technologies

IS Bayer - Advanced Materials Interfaces, 2022 - Wiley Online Library
Mucoadhesion is an extremely important field of adhesion science and the comprehensive
understanding and modulation of mucoadhesion can lead to lifesaving materials and …

A comprehensive insight on ocular pharmacokinetics

V Agrahari, A Mandal, V Agrahari, HM Trinh… - Drug delivery and …, 2016 - Springer
The eye is a distinctive organ with protective anatomy and physiology. Several
pharmacokinetics compartment models of ocular drug delivery have been developed for …

Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb

F Lallemand, P Daull, S Benita… - Journal of drug …, 2012 - Wiley Online Library
Topical ophthalmic delivery of active ingredients can be achieved using cationic
nanoemulsions. In the last decade, Novagali Pharma has successfully developed and …

Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma

K Zhang, L Zhang, RN Weinreb - Nature reviews Drug discovery, 2012 - nature.com
Blindness affects 60 million people worldwide. The leading causes of irreversible blindness
include age-related macular degeneration, retinal vascular diseases and glaucoma. The …

In situ formation of injectable chitosan-gelatin hydrogels through double crosslinking for sustained intraocular drug delivery

Y Song, N Nagai, S Saijo, H Kaji, M Nishizawa… - Materials Science and …, 2018 - Elsevier
Rapid clearance and low ocular bioavailability are drawbacks of conventional ophthalmic
eye drops. To increase the ocular drug resistance time and improve efficacy, an in situ …

Nanomedicine for the detection and treatment of ocular bacterial infections

X Huang, L Li, Z Chen, H Yu, X You, N Kong… - Advanced …, 2023 - Wiley Online Library
Ocular bacterial infection is a prevalent cause of blindness worldwide, with substantial
consequences for normal human life. Traditional treatments for ocular bacterial infections …

Carbohydrate polymer-based bioadhesive formulations and their potentials for the treatment of ocular diseases: a review

X Tang, J Liu, R Yan, Q Peng - International Journal of Biological …, 2023 - Elsevier
Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Nanomaterials for ocular drug delivery

S Liu, L Jones, FX Gu - Macromolecular bioscience, 2012 - Wiley Online Library
Efficient drug delivery to the eye remains a challenging task for pharmaceutical scientists.
Due to the various anatomical barriers and the clearance mechanisms prevailing in the eye …

[HTML][HTML] Advanced drug delivery and targeting technologies for the ocular diseases

J Barar, A Aghanejad, M Fathi, Y Omidi - BioImpacts: BI, 2016 - ncbi.nlm.nih.gov
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Introduction: Ocular targeted therapy has enormously been advanced by implementation of …