Urinary microbiome: yin and yang of the urinary tract

V Perez-Carrasco, A Soriano-Lerma… - Frontiers in cellular …, 2021 - frontiersin.org
The application of next generation sequencing techniques has allowed the characterization
of the urinary tract microbiome and has led to the rejection of the pre-established concept of …

The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

The inflammatory microenvironment and microbiome in prostate cancer development

KS Sfanos, S Yegnasubramanian, WG Nelson… - Nature Reviews …, 2018 - nature.com
Chronic inflammation promotes the development of several types of solid cancers and might
contribute to prostate carcinogenesis. This hypothesis partly originates in the frequent …

The microbiome of the urinary tract—a role beyond infection

SA Whiteside, H Razvi, S Dave, G Reid… - Nature Reviews …, 2015 - nature.com
Urologists rarely need to consider bacteria beyond their role in infectious disease. However,
emerging evidence shows that the microorganisms inhabiting many sites of the body …

Advances in understanding the human urinary microbiome and its potential role in urinary tract infection

ML Neugent, NV Hulyalkar, VH Nguyen, PE Zimmern… - MBio, 2020 - Am Soc Microbiol
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …

Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract

KA Kline, AL Lewis - Urinary tract infections: molecular …, 2017 - Wiley Online Library
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …

Urine is not sterile: use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder

EE Hilt, K McKinley, MM Pearce… - Journal of clinical …, 2014 - Am Soc Microbiol
Our previous study showed that bacterial genomes can be identified using 16S rRNA
sequencing in urine specimens of both symptomatic and asymptomatic patients who are …

The urinary tract microbiome in health and disease

IM Aragon, B Herrera-Imbroda, MI Queipo-Ortuño… - European urology …, 2018 - Elsevier
Context The urinary tract, previously considered a sterile body niche, has emerged as the
host of an array of bacteria in healthy individuals, revolutionizing the urology research field …

The human microbiome: our second genome

EA Grice, JA Segre - Annual review of genomics and human …, 2012 - annualreviews.org
The human genome has been referred to as the blueprint of human biology. In this review
we consider an essential but largely ignored overlay to that blueprint, the human …

Vaginal microbiome and its relationship to behavior, sexual health, and sexually transmitted diseases

FMT Lewis, KT Bernstein, SO Aral - Obstetrics & Gynecology, 2017 - journals.lww.com
The vaginal microbiota has great significance in maintaining vaginal health and protecting
the host from disease. Recent advances in molecular techniques and informatics allow …