Ruminant animals house a dense and diverse community of microorganisms in their rumen,
an enlarged compartment in their stomach, which provides a supportive environment for the …

Highlights•Formate is an ideal mediator between the physicochemical and biological
realms.•Formate can be efficiently produced from various highly available …

Subcellular compartments often serve to store nutrients or sequester labile or toxic
compounds. As bacteria mostly do not possess membrane-bound organelles, they often …

Cancers that appear pathologically similar often respond differently to the same drug
regimens. Methods to better match patients to drugs are in high demand. We demonstrate a …

Intracellular organization is a key factor in cell metabolism. Cells have evolved various
organizational systems to solve the challenges of toxic pathway intermediates, competing …

Bacterial microcompartments (BMCs) are proteinaceous organelles involved in both
autotrophic and heterotrophic metabolism. All BMCs share homologous shell proteins but …

Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of
cellular life, display defined shapes and complex internal organization, showcasing a highly …

Bacterial microcompartments are proteinaceous complexes that catalyze metabolic
pathways in a manner reminiscent of organelles. Although microcompartment structure is …

Bacterial microcompartments (MCPs) are sophisticated protein-based organelles used to
optimize metabolic pathways. They consist of metabolic enzymes encapsulated within a …

As synthetic pathways built from exogenous enzymes become more complicated, the
probability of encountering undesired interactions with host organisms increases, thereby …