Cellular function and molecular structure of ecto-nucleotidases

H Zimmermann, M Zebisch, N Sträter - Purinergic signalling, 2012 - Springer
Ecto-nucleotidases play a pivotal role in purinergic signal transmission. They hydrolyze
extracellular nucleotides and thus can control their availability at purinergic P2 receptors …

[HTML][HTML] Host immune responses to salivary components-a critical facet of tick-host interactions

A Ali, I Zeb, A Alouffi, H Zahid, MM Almutairi… - Frontiers in Cellular …, 2022 - frontiersin.org
Tick sialome is comprised of a rich cocktail of bioactive molecules that function as a tool to
disarm host immunity, assist blood-feeding, and play a vibrant role in pathogen …

Argasid and ixodid systematics: implications for soft tick evolution and systematics, with a new argasid species list

BJ Mans, J Featherston, M Kvas, KA Pillay… - Ticks and tick-borne …, 2019 - Elsevier
The systematics of the genera and subgenera within the soft tick family Argasidae is not
adequately resolved. Different classification schemes, reflecting diverse schools of scientific …

[HTML][HTML] A Deep Insight into the Sialotranscriptome of the Gulf Coast Tick, Amblyomma maculatum

S Karim, P Singh, JMC Ribeiro - PloS one, 2011 - journals.plos.org
Background Saliva of blood sucking arthropods contains compounds that antagonize their
hosts' hemostasis, which include platelet aggregation, vasoconstriction and blood clotting; …

An insight into the sialome of blood-feeding Nematocera

JMC Ribeiro, BJ Mans, B Arcà - Insect biochemistry and molecular biology, 2010 - Elsevier
Within the Diptera and outside the suborder Brachycera, the blood-feeding habit occurred at
least twice, producing the present day sand flies, and the Culicomorpha, including the …

Tick salivary secretion as a source of antihemostatics

J Chmelar, E Calvo, JHF Pedra, IMB Francischetti… - Journal of …, 2012 - Elsevier
Ticks are mostly obligatory blood feeding ectoparasites that have an impact on human and
animal health. In addition to direct damage due to feeding, some tick species serve as the …

[HTML][HTML] TickSialoFam (TSFam): a database that helps to classify tick salivary proteins, a review on tick salivary protein function and evolution, with considerations on …

JMC Ribeiro, BJ Mans - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Tick saliva contains a complex mixture of peptides and non-peptides that counteract their
hosts' hemostasis, immunity, and tissue-repair reactions. Recent transcriptomic studies have …

[HTML][HTML] Nuttalliella namaqua: A Living Fossil and Closest Relative to the Ancestral Tick Lineage: Implications for the Evolution of Blood-Feeding in Ticks

BJ Mans, D de Klerk, R Pienaar, AA Latif - PloS one, 2011 - journals.plos.org
Ticks are monophyletic and composed of the hard (Ixodidae) and soft (Argasidae) tick
families, as well as the Nuttalliellidae, a family with a single species, Nuttalliella namaqua …

Understanding pathogen survival and transmission by arthropod vectors to prevent human disease

C Barillas-Mury, JMC Ribeiro, JG Valenzuela - Science, 2022 - science.org
Many endemic poverty-associated diseases, such as malaria and leishmaniasis, are
transmitted by arthropod vectors. Pathogens must interact with specific molecules in the …

Platelet aggregation inhibitors from hematophagous animals

IMB Francischetti - Toxicon, 2010 - Elsevier
Salivary glands from blood-sucking animals (eg, mosquitoes, bugs, sand flies, fleas, ticks,
leeches, hookworms, bats) are a rich source of bioactive molecules that counteract …