Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a
complex disease involving more than airflow obstruction. Airflow obstruction has profound …

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death
worldwide and has few effective therapies. It is characterized by anomalous and persistent …

Chronic obstructive pulmonary disease is a leading cause of death and disability, but has
only recently been extensively explored from a cellular and molecular perspective. There is …

Chronic obstructive pulmonary disease (COPD) is a major and increasing global health
problem that is now a leading cause of death. COPD is associated with a chronic …

Inhaled corticosteroids (ICS) are important in reducing exacerbation frequency associated
with chronic obstructive pulmonary disease (COPD). However, little is known about the risk …

Exacerbations of chronic obstructive pulmonary disease (COPD) are an increasing cause of
hospitalisations and are associated with accelerated progression of airflow obstruction …

Chronic obstructive pulmonary disease is a highly prevalent, complex disease, usually
caused by cigarette smoke. It causes serious morbidity and mortality and costs the global …

Aging is a natural process characterized by progressive functional impairment and reduced
capacity to respond appropriately to environmental stimuli and injury. The incidence of two …

The lungs are a major site of entry of pathogens into the body and thus require rapid and
effective innate responses to prevent pathogens establishing infection and to limit their …

Maintaining an airway clear of inhaled particles, pathogens, and cellular debris is
paramount for lung homeostasis. In healthy individuals, the phagocytes of the innate …