Background: Contemporary studies suggest that familial hypercholesterolemia (FH) is more
frequent than previously reported and increasingly recognized as affecting individuals of all …

Objectives Heterozygous familial hypercholesterolaemia (FH) confers a significant risk for
premature cardiovascular disease (CVD). However, the estimated prevalence of FH varies …

Background Research on the integration of artificial intelligence (AI) into community-based
primary health care (CBPHC) has highlighted several advantages and disadvantages in …

Natural language processing (NLP) is a set of automated methods to organise and evaluate
the information contained in unstructured clinical notes, which are a rich source of real-world …

Optimal care for familial hypercholesterolaemia (FH) requires patient-centred management,
multidisciplinary teamwork, involvement of primary care practitioners, patient networks …

Because polygenic risk scores (PRSs) for coronary heart disease (CHD) are derived from
mainly European ancestry (EA) cohorts, their validity in African ancestry (AA) and Hispanic …

Familial hypercholesterolemia (FH) is a dominantly inherited genetic disorder affecting
approximately 1 in 250 individuals. It is characterized by markedly elevated low-density …

In this paper, we review the evolution of the field of public health genomics in the United
States in the past two decades. Public health genomics focuses on effective and responsible …

Importance Population-based assessment of disease risk associated with gene variants
informs clinical decisions and risk stratification approaches. Objective To evaluate the …

The transition from analog to digital technologies in clinical laboratory genomics is ushering
in an era of “big data” in ways that will exceed human capacity to rapidly and reproducibly …