Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …

Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …

The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …

Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat
stomach and is involved in a novel system for regulating GH release. Although previous …

Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …

Synthetic agonists of the growth hormone secretagogue receptor (GHSR) rejuvenate the
pulsatile pattern of GH-release in the elderly, and increase lean but not fat mass in obese …

The mechanisms for controlling food intake involve mainly an interplay between gut, brain,
and adipose tissue (AT), among the major organs. Parasympathetic, sympathetic, and other …

Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …

Our understanding of the physiological systems that regulate food intake and body weight
has increased immensely over the past decade. Brain centres, including the hypothalamus …

Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth
hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n …