Long-acting parenteral drug delivery systems for the treatment of chronic diseases

AB Jindal, AR Bhide, S Salave, D Rana… - Advanced Drug Delivery …, 2023 - Elsevier
The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

Midazolam: an essential palliative care drug

E Prommer - Palliative care and social practice, 2020 - journals.sagepub.com
Midazolam is a commonly used benzodiazepine in palliative care and is considered one of
the four essential drugs needed for the promotion of quality care in dying patients. Acting on …

Fostemsavir in adults with multidrug-resistant HIV-1 infection

M Kozal, J Aberg, G Pialoux, P Cahn… - … England Journal of …, 2020 - Mass Medical Soc
Background Among some patients with human immunodeficiency virus type 1 (HIV-1)
infection who have undergone multiple antiretroviral therapies and have limited options for …

Efavirenz: history, development and future

B Costa, N Vale - Biomolecules, 2022 - mdpi.com
Efavirenz (Sustiva®) is a first-generation non-nucleoside reverse transcriptase inhibitor
(NNRTI) used to treat human immunodeficiency virus (HIV) type 1 infection or to prevent the …

Drug‐drug interactions with candidate medications used for COVID‐19 treatment: an overview

H Rezaee, F Pourkarim… - Pharmacology …, 2021 - Wiley Online Library
Drug‐drug interaction (DDI) is a common clinical problem that has occurred as a result of the
concomitant use of multiple drugs. DDI may occur in patients under treatment with …

Advancing HIV broadly neutralizing antibodies: from discovery to the clinic

DA Spencer, MB Shapiro, NL Haigwood… - Frontiers in Public …, 2021 - frontiersin.org
Despite substantial progress in confronting the global HIV-1 epidemic since its inception in
the 1980s, better approaches for both treatment and prevention will be necessary to end the …

Protease inhibitors for the treatment of HIV/AIDS: recent advances and future challenges

C Voshavar - Current Topics in Medicinal Chemistry, 2019 - ingentaconnect.com
Acquired Immunodeficiency Syndrome (AIDS) is a chronic disease characterized by multiple
life-threatening illnesses caused by a retro-virus, Human Immunodeficiency Virus (HIV). HIV …

Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment

Y Gong, S Haque, P Chowdhury, TJ Cory… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Drugs used in HIV treatment; all protease inhibitors, some non-nucleoside
reverse transcriptase inhibitors, and pharmacoenhancers ritonavir and cobicistat can inhibit …

Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic system by lipophilic ester prodrug approach

C Qin, YJ Chu, W Feng, C Fromont, S He, J Ali… - Journal of Controlled …, 2021 - Elsevier
The combined antiretroviral therapy (cART) can efficiently suppress HIV replication, but the
cessation of cART usually results in viral rebound, mostly due to the presence of viral …

[HTML][HTML] Drug–Drug Interactions in Nosocomial Infections: An Updated Review for Clinicians

S Hîncu, MM Apetroaei, G Ștefan, AI Fâcă, AL Arsene… - Pharmaceutics, 2024 - mdpi.com
Prevention, assessment, and identification of drug–drug interactions (DDIs) represent a
challenge for healthcare professionals, especially in nosocomial settings. This narrative …