An Overview of Current Knowledge on in vitro Babesia Cultivation for Production of Live Attenuated Vaccines for Bovine Babesiosis in Mexico

JA Alvarez, C Rojas, JV Figueroa - Frontiers in veterinary science, 2020 - frontiersin.org
The instrumentation of the in vitro culture system has allowed researchers to learn more
about the metabolic and growth behavior of Babesia spp. The various applications for in …

Major Surface Antigens in Zoonotic Babesia

S Delbecq - Pathogens, 2022 - mdpi.com
Human babesiosis results from a combination of tick tropism for humans, susceptibility of a
host to sustain Babesia development, and contact with infected ticks. Climate modifications …

Babesia, Theileria, Plasmodium and hemoglobin

D Sojka, M Jalovecká, J Perner - Microorganisms, 2022 - mdpi.com
The Propagation of Plasmodium spp. and Babesia/Theileria spp. vertebrate blood stages
relies on the mediated acquisition of nutrients available within the host's red blood cell …

Identification and characterization of extracellular vesicles from red cells infected with Babesia divergens and Babesia microti

D Beri, M Rodriguez, M Singh, Y Liu… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesiosis is a zoonosis and an important blood-borne human parasitic infection that has
gained attention because of its growing infection rate in humans by transfer from animal …

Specific and sensitive diagnosis of Babesia microti active infection using monoclonal antibodies to the immunodominant antigen BmGPI12

J Gagnon, S Timalsina, JY Choi, M Chand… - Journal of Clinical …, 2022 - Am Soc Microbiol
The apicomplexan pathogen Babesia microti is responsible for most cases of human
babesiosis worldwide. The disease, which presents as a malaria-like illness, is potentially …

Cytochrome b Drug Resistance Mutation Decreases Babesia Fitness in the Tick Stages But Not the Mammalian Erythrocytic Cycle

JE Chiu, I Renard, S George, AC Pal… - The Journal of …, 2022 - academic.oup.com
Human babesiosis is an emerging tick-borne malaria-like illness caused by Babesia
parasites following their development in erythrocytes. Here, we show that a mutation in the …

Plasmepsin-like Aspartyl Proteases in Babesia

P Šnebergerová, P Bartošová-Sojková, M Jalovecká… - Pathogens, 2021 - mdpi.com
Apicomplexan genomes encode multiple pepsin-family aspartyl proteases (APs) that
phylogenetically cluster to six independent clades (A to F). Such diversification has been …

Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti

M Chand, JY Choi, AC Pal, P Singh… - Frontiers in Cellular …, 2022 - frontiersin.org
The significant rise in the number of tick-borne diseases represents a major threat to public
health worldwide. One such emerging disease is human babesiosis, which is caused by …

Identification of Babesia microti immunoreactive antigens by phage display cDNA screen

T Hanada, MA Empitu, GI Mines, Q Ma… - Infection and …, 2024 - Am Soc Microbiol
Human babesiosis is a malaria-like illness caused by protozoan parasites of the genus
Babesia. Babesia microti is responsible for most cases of human babesiosis in the United …

Four-Dimensional Characterization of the Babesia divergens Asexual Life Cycle, from the Trophozoite to the Multiparasite Stage

JJ Conesa, E Sevilla, MC Terrón, LM González, J Gray… - MSphere, 2020 - Am Soc Microbiol
Babesia is an apicomplexan parasite of significance that causes the disease known as
babesiosis in domestic and wild animals and in humans worldwide. Babesia infects …