The locus coeruleus-norepinephrine (LC-NE) system is involved in many brain functions
and neurological disorders. In this review we discuss how LC-NE signaling affects the …

Many studies in intact animals have shown that locally applied or synaptically released
norepinephrine (NE) can enhance individual neuron and neural network responses to …

Motor and premotor cortices are crucial for the control of movements. However, we still know
little about how these areas contribute to higher-order motor control, such as deciding which …

The world view of rodents is largely determined by sensation on two length scales. One is
within the animal's peri-personal space; sensorimotor control on this scale involves active …

Sensory stimuli can trigger an orienting reflex (response) by which animals move the head
to position their sensors (eg, eyes, pinna, whiskers). Orienting responses may be important …

Essential to spatial orientation in the natural environment is a dynamic representation of
direction and distance to objects. Despite the importance of 3D spatial localization to parse …

After been exposed to the visual input, in the first year of life, the brain experiences subtle
but massive changes apparently crucial for communicative/emotional and social human …

A fundamental goal of systems neuroscience is to understand the neural mechanisms
underlying decision making. The midbrain superior colliculus (SC) is known to be central to …

The superior colliculus (SC), a conserved midbrain node with extensive long-range
connectivity throughout the brain, is a key structure for innate behaviors. Descending cortical …

Multisensory integration is a process by which signals from different sensory modalities are
combined to facilitate detection and localization of external events. One substrate for …