A pH-Responsive Nanoplatform Based on Magnetic Mesoporous Silica Nanoparticles for Enhanced Treatment of Pancreatic Cancer

G Qi, S Wang, Q Yin, Z Zhang, X Wen… - ACS Applied Nano …, 2023 - ACS Publications
This study presents the pH-responsive nanoplatform DOX@ M-MSN-5-FAM@ PDA (DM-F@
P) to improve the treatment of pancreatic cancer. DM-F@ P is a combination of magnetic …

Zwitterionic Strategy to Stabilize Self‐Immolative Polymer Nanoarchitecture under Physiological pH for Drug Delivery In Vitro and In Vivo

S Pathan, M Jayakannan - Advanced Healthcare Materials, 2024 - Wiley Online Library
The major bottleneck in using polymer nanovectors for biomedical application, particularly
those based on self‐immolative poly (amino ester)(PAE), lies in their uncontrolled …

Dual stimuli-responsive biotinylated polymer–drug conjugate for dual drug delivery

D Ghosh, A Khan, S Bag, AI Mallick… - Journal of Materials …, 2024 - pubs.rsc.org
Stimuli-responsive nanoscale polymer–drug conjugates are one of the most promising
alternatives in the realm of advanced therapeutics, rendering several characteristics such as …

Degradable Theranostic Polyurethane for Macrophage-Targeted Antileishmanial Drug Delivery

S Bag, A Seth, D Ghosh, R Datta, P De - Biomacromolecules, 2025 - ACS Publications
The present investigation aims to develop a reactive oxygen species (ROS) and esterase-
responsive biodegradable mannosylated polyurethane to effectively deliver the …

Biotinylated Theranostic Amphiphilic Polyurethane for Targeted Drug Delivery

S Bag, MP Gadpayle, D Ghosh, S Maiti… - Biomacromolecules, 2024 - ACS Publications
In the area of drug delivery aided by stimuli-responsive polymers, the biodegradability of
nanocarriers is one of the major challenges that needs to be addressed with the utmost …

Size- and Shape-controlled Biodegradable Polymer Brushes Based on l-Amino Acid for Intracellular Drug Delivery and Deep-Tissue Penetration

UA Gavhane, DC Joshi, M Jayakannan - Biomacromolecules, 2024 - ACS Publications
We report size-and shape-controlled polymer brushes based on l-amino acid bioresource
and study the role of polymer topology on the enzymatic biodegradation and deep-tissue …

Melt Polycondensation Strategy to Access Unexplored l-Amino Acid and Sugar Copolymers

D Chandra Joshi, UA Gavhane… - …, 2024 - ACS Publications
Biodegradable polymers from bioresources are highly in demand for the development of
sustainable polymer platforms for commodity plastics and in the biomedical field. Here, an …

Manganese-Doped Mesoporous Magnetic Nanocarriers for Cancer Treatment

X Zhou, X He, Z Dong, Y Wang, C Hu… - ACS Applied Nano …, 2024 - ACS Publications
To achieve maximum curative effects and minimize side effects in trimodal synergistic
cooperative tumor therapies, we propose a strategy of photothermal (PTT)-chemodynamic …

Structural Engineering of l-Aspartic Amphiphilic Polyesters for Enzyme-Responsive Drug Delivery and Bioimaging in Cancer Cells

M Khuddus, UA Gavhane, M Jayakannan - ACS Polymers Au, 2024 - ACS Publications
Design and development of amphiphilic polyesters based on bioresources are very
important to cater to the ever-growing need for biodegradable polymers in biomedical …

Photo and pH dual stimuli-responsive block copolymer micelles with defined incorporation of o-nitrobenzyl units in poly (ɛ-caprolactone) block for controlled release

SV Avhad, SN Choudhari, AV Ambade - European Polymer Journal, 2024 - Elsevier
A series of dual stimuli-responsive block copolymers with varying content of photocleavable
o-nitrobenzyl (ONB) ester group pendent in the hydrophobic poly (ɛ-caprolactone) block …