Bronchopulmonary dysplasia: where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease

B Thébaud, SH Abman - American journal of respiratory and critical …, 2007 - atsjournals.org
Bronchopulmonary dysplasia and emphysema are significant global health problems at the
extreme stages of life. Both are characterized by arrested alveolar development or loss of …

Pathology of bronchopulmonary dysplasia

JJ Coalson - Seminars in perinatology, 2006 - Elsevier
Over the past three decades, advances in prenatal and neonatal intensive care have
contributed to marked improvements in survival rates for extremely immature infants born …

Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury

SY Ahn, WS Park, YE Kim, DK Sung, SI Sung… - … & molecular medicine, 2018 - nature.com
We previously reported the role of vascular endothelial growth factor (VEGF) secreted by
mesenchymal stem cells (MSCs) in protecting against neonatal hyperoxic lung injuries …

Animal models of bronchopulmonary dysplasia. The term rat models

M O'Reilly, B Thébaud - American Journal of Physiology …, 2014 - journals.physiology.org
Bronchopulmonary dysplasia (BPD) is the chronic lung disease of prematurity that affects
very preterm infants. Although advances in perinatal care have enabled the survival of …

Maternal preeclampsia predicts the development of bronchopulmonary dysplasia

AR Hansen, CM Barnés, J Folkman, TF McElrath - The Journal of pediatrics, 2010 - Elsevier
OBJECTIVE: To test the hypothesis that exposure to preeclampsia is associated with an
increased risk of bronchopulmonary dysplasia (BPD). STUDY DESIGN: A prospective cohort …

Pitfalls, problems, and progress in bronchopulmonary dysplasia

A Bhandari, V Bhandari - Pediatrics, 2009 - publications.aap.org
Bronchopulmonary dysplasia is a chronic lung disease associated with premature birth and
characterized by early lung injury. In this review we discuss some pitfalls, problems, and …

Intraperitoneal injection of MSC-derived exosomes prevent experimental bronchopulmonary dysplasia

RK Braun, C Chetty, V Balasubramaniam… - Biochemical and …, 2018 - Elsevier
Mesenchymal stromal cell (MSC) derived exosomes mediate tissue protection and
regeneration in many injuries and diseases by modulating cell protein production, protecting …

Intrauterine growth restriction decreases pulmonary alveolar and vessel growth and causes pulmonary artery endothelial cell dysfunction in vitro in fetal sheep

PJ Rozance, GJ Seedorf, A Brown… - … of Physiology-Lung …, 2011 - journals.physiology.org
Intrauterine growth restriction (IUGR) increases the risk for bronchopulmonary dysplasia
(BPD). Abnormal lung structure has been noted in animal models of IUGR, but whether …

The cellular basis for diverse responses to oxygen

NS Chandel, GRS Budinger - Free Radical Biology and Medicine, 2007 - Elsevier
Mammalian cells have divergent responses to varying oxygen levels. Cells exposed to low
oxygen levels (hypoxia) activate the transcription factor hypoxia-inducible factor-1 (HIF-1) as …

Hyperoxia reduces bone marrow, circulating, and lung endothelial progenitor cells in the developing lung: implications for the pathogenesis of bronchopulmonary …

V Balasubramaniam, CF Mervis… - … of Physiology-Lung …, 2007 - journals.physiology.org
Hyperoxia disrupts vascular and alveolar growth of the developing lung and contributes to
the development of bronchopulmonary dysplasia (BPD). Endothelial progenitor cells (EPC) …