The dermis is primarily composed of the extracellular matrix (ECM) and fibroblasts. During
the aging process, the dermis undergoes significant changes. Collagen, which is a major …

Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within
subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal …

As the most voluminous organ of the body that is exposed to the outer environment, the skin
suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features …

Skin aging is a complex process influenced by intrinsic and extrinsic factors. Together, these
factors affect the structure and function of the epidermis and dermis. Histologically, aging …

Collagen-based supplements have become a keystone in the management of the ageing
process, with proven ability to repair skin damage, bestowing a youthful and healthy …

The normal course of aging alters the harmonious, symmetrical, and balanced facial
features found in youth, not only impacting physical attractiveness but also influencing self …

INTRODUCTION Fibroblasts produce extracellular matrix (ECM) molecules that regulate
tissue strength and resilience. Imbalanced ECM maintenance leads to tissue dysfunction …

The primary function of the skin is to act as a barrier against insults from the environment,
and its unique structure reflects this. The skin is composed of two layers: the epidermal outer …

Skin aging is a multifaceted process that involves intrinsic and extrinsic mechanisms that
lead to various structural and physiological changes in the skin. Intrinsic aging is associated …

Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …