Biological activity of recently discovered halogenated marine natural products

GW Gribble - Marine drugs, 2015 - mdpi.com
This review presents the biological activity—antibacterial, antifungal, anti-parasitic, antiviral,
antitumor, antiinflammatory, antioxidant, and enzymatic activity—of halogenated marine …

Naturally Occurring Organohalogen Compounds—A Comprehensive Review

GW Gribble - Naturally Occurring Organohalogen Compounds, 2023 - Springer
The present volume is the third in a trilogy that documents naturally occurring
organohalogen compounds, bringing the total number—from fewer than 25 in 1968—to …

Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria

M Tadesse, J Svenson, K Sepčić… - Journal of natural …, 2014 - ACS Publications
Pulmonarins A and B are two new dibrominated marine acetylcholinesterase inhibitors that
were isolated and characterized from the sub-Arctic ascidian Synoicum pulmonaria …

Indole alkaloids from marine sources as potential leads against infectious diseases

PHB França, DP Barbosa, DL da Silva… - BioMed research …, 2014 - Wiley Online Library
Indole alkaloids comprise a large and complex class of natural products found in a variety of
marine sources. Infectious diseases remain a major threat to public health, and in the …

[HTML][HTML] The Mechanism of Action of L-Tyrosine Derivatives against Chikungunya Virus Infection In Vitro Depends on Structural Changes

V Loaiza-Cano, E Hernández-Mira… - International Journal of …, 2024 - mdpi.com
Although the disease caused by chikungunya virus (CHIKV) is of great interest to public
health organizations around the world, there are still no authorized antivirals for its …

[PDF][PDF] Bromotyrosine derivatives from marine sponges inhibit the HIV-1 replication in vitro

LG GÓMEZ-ARCHILA, W Zapata, E Galeano… - Vitae, 2014 - redalyc.org
Antecedentes: La infección por el virus de la inmunodeficiencia humana tipo 1 (VIH-1) y el
síndrome de inmunodeficiencia adquirida son los principales problemas de salud pública …

[HTML][HTML] Bromotyrosine-derived alkaloids from the Caribbean sponge Aplysina lacunosa

Q Göthel, T Sirirak, M Köck - Beilstein Journal of Organic …, 2015 - beilstein-journals.org
Three new bromotyrosine-derived alkaloids 14-debromo-11-deoxyfistularin-3 (1), aplysinin
A (2), and aplysinin B (3), together with 15 known compounds (4–18) were isolated from the …

Synthesis and trypanocide activity of chloro-l-tyrosine and bromo-l-tyrosine derivatives

M Pastrana Restrepo, E Galeano Jaramillo… - Medicinal Chemistry …, 2018 - Springer
Twenty-two halogenated l-tyrosine derivatives were synthesized to examine new
substances for the treatment of Chagas disease. The synthesis of these derivatives with …

[HTML][HTML] Estudio fitoquímico y evaluación de la actividad antioxidante y leishmanicida de la especie Pilocarpus alvaradoi (Rutaceae)

FJ Marin, OL Torres, SM Robledo… - Información tecnológica, 2018 - SciELO Chile
Se realizó el estudio fitoquímico y se evaluó la actividad antioxidante y leishmanicida de la
especie Pilocarpus alvaradoi. La identificación de los compuestos se realizó mediante el …

In vitro and in silico anti-Arboviral activities of Dihalogenated phenolic Derivates of L-tyrosine

V Loaiza-Cano, LM Monsalve-Escudero, MP Restrepo… - Molecules, 2021 - mdpi.com
Despite the serious public health problem represented by the diseases caused by dengue
(DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses, there are still no specific licensed …