Estimation of drug–excipient interactions is a crucial step in preformulation studies of drug
development to achieve consistent stability, bioavailability and manufacturability of solid …

Sildenafil is a potent selective, reversible inhibitor of phosphodiesterase type 5 (PDE5)
approved for the treatment of erectile dysfunction and pulmonary arterial hypertension …

Abstract Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is a phytochemical constituent
from the polyphenols group commonly found in whole grains, spinach, parsley, grapes and …

Pulmonary delivery of vasodilators is a promising alternative for the intravenous and oral
treatment of pulmonary arterial hypertension (PAH). The aim of this study was to design and …

The oral administration of sildenafil citrate (SC) for the treatment of pulmonary arterial
hypertension is associated with several drawbacks. The study aimed to design and …

Background The aim of the study was to evaluate the suitability of triclosan (TCS) and
flurbiprofen (FLB) with poly-ε-caprolactone (PCL), chitosan (CS), and Kolliphor® P188 (KP) …

The past decades have witnessed tremendous expansion in utilization of plant-derived
medicines as resveratrol (RES) in treating several diseases like idiopathic pulmonary …

Ketoconazole (KTZ) is an antifungal agent responsible for the inhibition of 14-α-demethylase
sterol. The drug–excipient compatibility studies play an important role in pharmaceutical …

The aim of the present study was to prepare the particulate taste-masking system to mask
the bitter taste of sildenafil citrate (SC), a well-known phosphodiesterase-5 inhibitor used for …

Hydroxychloroquine is effectively used in the treatment for malaria, lupus erythematosus and
rheumatoid arthritis. The study of drug–excipient compatibility is an important tool for the …