Computer vision quantification of whole-body Parkinsonian bradykinesia using a large multi-site population

G Morinan, Y Dushin, G Sarapata… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is a common neurological disorder, with bradykinesia being one of
its cardinal features. Objective quantification of bradykinesia using computer vision has the …

Association between hearing sensitivity and dopamine transporter availability in Parkinson's disease

E Garasto, A Stefani, M Pierantozzi… - Brain …, 2023 - academic.oup.com
In a previous study, we observed:(i) significant hearing function impairment, assessed with
pure tone audiometry and distortion product otoacoustic emissions, in patients with …

The concept of motor reserve in Parkinson's disease: new wine in old bottles?

MC Hoenig, T van Eimeren, V Dzialas… - Movement …, 2023 - juser.fz-juelich.de
Across neurodegenerative diseases, such as Parkinson's disease (PD) and Alzheimer's
disease (AD), a disparity between the clinical expression and the extent of …

[HTML][HTML] Biomarkers and non-motor symptoms as a function of motor symptom asymmetry in early Parkinson's disease

P Voruz, IM Constantin, JA Péron - Neuropsychologia, 2022 - Elsevier
Introduction The longitudinal trajectories of cognitive-neuropsychiatric symptoms from the
early stages of Parkinson's disease, as a function of motor symptom asymmetry at the onset …

Circular walking is useful for assessing the risk of falls in early progressive supranuclear palsy

M Ohara, K Hirata, T Matsubayashi, Q Chen… - Journal of …, 2024 - Springer
Background Progressive supranuclear palsy (PSP) is characterized by early onset postural
instability and frequent falls. Circular walking necessitates dynamic postural control, which is …

Structural underpinnings and long-term effects of resilience in Parkinson's disease

V Dzialas, MC Hoenig, S Prange, GN Bischof… - npj Parkinson's …, 2024 - nature.com
Resilience in neuroscience generally refers to an individual's capacity to counteract the
adverse effects of a neuropathological condition. While resilience mechanisms in …

Microstructural degeneration of the corpus callosum in Parkinson's disease with unilateral onset: A free-water imaging study

J Chen, J Wu, C Zhou, H Wu, T Guo, X Bai… - ACS Chemical …, 2024 - ACS Publications
Background: Motor symptom laterality is an important clinical feature of PD that not only
manifests as lateral limb dysfunction but also affects the nonmotor symptoms and the …

Long-term levodopa ameliorates sequence effect in simple, but not complex walking in early Parkinson's disease patients

M Ohara, K Hirata, M Hallett, T Matsubayashi… - Parkinsonism & related …, 2023 - Elsevier
Background The sequence effect (SE) is characterized by the progressive decrement of
movements and is often observed in Parkinson's disease (PD) patients. While acute effect of …

Topological patterns of motor networks in Parkinson's disease with different sides of onset: A resting-state-informed structural connectome study

X Zhang, R Li, Y Xia, H Zhao, L Cai, J Sha… - Frontiers in Aging …, 2022 - frontiersin.org
Parkinson's disease (PD) has a characteristically unilateral pattern of symptoms at onset and
in the early stages; this lateralization is considered a diagnostically important diagnosis …

Does Motor Symptoms Asymmetry Predict Motor Outcome of Subthalamic Deep Brain Stimulation in Parkinson's Disease Patients?

F Bove, F Cavallieri, A Castrioto, S Meoni… - Frontiers in Human …, 2022 - frontiersin.org
Background In Parkinson's disease (PD), the side of motor symptoms onset may influence
disease progression, with a faster motor symptom progression in patients with left side …