Coated pellets for oral colon delivery

L Palugan, M Cerea, L Zema, A Gazzaniga… - Journal of Drug Delivery …, 2015 - Elsevier
Because of their spherical or pseudo-spherical shape, uniform size and smooth surface,
pellets are of particular interest for use as cores in the manufacturing of coated oral delivery …

Colon targeted oral drug delivery system based on alginate-chitosan microspheres loaded with icariin in the treatment of ulcerative colitis

QS Wang, GF Wang, J Zhou, LN Gao, YL Cui - International journal of …, 2016 - Elsevier
In recent years, oral colon specific drug delivery system has been paid more attention in the
treatment of inflammatory bowel disease (IBD). As the special pH condition in …

Preparation and characterization of pectin/chitosan beads containing porous starch embedded with doxorubicin hydrochloride: A novel and simple colon targeted …

J Zhu, L Zhong, W Chen, Y Song, Z Qian, X Cao… - Food …, 2019 - Elsevier
The objective of this study was to design a simple, colon targeted drug delivery system by
using porous starch (PS), pectin and chitosan. Porous maize starch was prepared by …

[图书][B] Chitin and chitosan derivatives: advances in drug discovery and developments

SK Kim - 2013 - books.google.com
A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the
exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and …

Retrograded starch/pectin coated gellan gum-microparticles for oral administration of insulin: A technological platform for protection against enzymatic degradation …

AB Meneguin, E Beyssac, G Garrait, H Hsein… - European Journal of …, 2018 - Elsevier
Gellan gum microparticles coated with colon-specific films based on retrograded starch and
pectin was developed for enhancing the oral release of insulin (INS). The system developed …

Biomaterial‐Derived Calcium Carbonate Nanoparticles for Enteric Drug Delivery

D Render, T Samuel, H King, M Vig… - Journal of …, 2016 - Wiley Online Library
Oral drug delivery systems provide the most convenient, noninvasive, readily acceptable
alternatives to parenteral systems. In the current work, eggshell‐derived calcium carbonate …

Development of a polysaccharide based multi-unit nanofiber mat for colon-targeted sustained release of salmon calcitonin

K Feng, C Li, YS Wei, MH Zong, H Wu… - Journal of colloid and …, 2019 - Elsevier
Advances in pharmaceutical technology have promoted the development of colon-targeted
delivery system for oral administration of bioactive peptides or proteins to enhance their …

Electrospun core-shell structured nanofilm as a novel colon-specific delivery system for protein

P Wen, K Feng, H Yang, X Huang, MH Zong… - Carbohydrate …, 2017 - Elsevier
A novel core-shell structured nanofilm for the delivery of protein to the colon was developed
by coaxial electrospinning using bovine serum albumin (BSA) as protein model. Firstly, the …

Preparation and characterization of electrospun colon-specific delivery system for quercetin and its antiproliferative effect on cancer cells

P Wen, MH Zong, TG Hu, L Li, H Wu - Journal of agricultural and …, 2018 - ACS Publications
To improve the oral bioavailability of quercetin (Q) and achieve colon-specific release, a
core–sheath electrospun fiber mat containing Q-loaded chitosan nanoparticle (Q-loaded …

Fabrication and characterization of shellac nanofibers with colon-targeted delivery of quercetin and its anticancer activity

SF Li, TG Hu, YB Jin, H Wu - International Journal of Biological …, 2024 - Elsevier
In this study, the feasibility of shellac nanofibers as carrier system for colonic delivery of
quercetin was evaluated. Firstly, the nanofibers without and with different amounts (2.5 …