Radiotherapy (RT) remains one of the current main treatment strategies for many types of
cancer. However, how to improve RT efficiency while reducing its side effects is still a large …

Preoperative neoadjuvant chemoradiotherapy (nCRT) is a standard treatment for locally
advanced rectal cancer (LARC) patients, yet little is known about the mediators underlying …

Currently, breast carcinoma is the most common form of malignancy and the main cause of
cancer mortality in women worldwide. The metastasis of cancer cells from the primary tumor …

PARP inhibitors are approved for treating advanced prostate cancers (APC) with various
defective DNA repair genes; however, further studies to clinically qualify predictive …

The limited efficacy of radiotherapy leads to radio‐resistance and high rates of tumor
recurrence and metastasis, which is caused by tumor hypoxia, rapid DNA damage repair …

The blood–brain barrier (BBB) severely blocks the intracranial accumulation of most
systemic drugs. Inspired by the contribution of the bacterial outer membrane to Escherichia …

The protooncoprotein N-Myc, which is overexpressed in approximately 25% of
neuroblastomas as the consequence of MYCN gene amplification, has long been postulated …

Radiotherapy remains an effective conventional method of treatment for patients with
cancer. However, the clinical efficacy of radiotherapy is compromised by the development of …

Triple-negative breast cancer (TNBC) is the most violent class of tumor and accounts for 20–
24% of total breast carcinoma, in which frequently rare mutation occurs in high frequency …

Receptor‐mediated vesicular transport has been extensively developed to penetrate the
blood‐brain barrier (BBB) and has emerged as a class of powerful brain‐targeting delivery …