Astrocytes are the most numerous type of neuroglia in the brain and have a predominant
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …

Astrocytes are the most abundant cell type in the CNS (central nervous system). They exert
multiple functions during development and in the adult CNS that are essential for brain …

In the mammalian brain, perivascular astrocytes (PAs) closely juxtapose blood vessels and
are postulated to have important roles in the control of vascular physiology, including …

Absence of the astrocyte-specific membrane protein MLC1 is responsible for
megalencephalic leukoencephalopathy with subcortical cysts (MLC), a rare type of …

Marked elevation in the brain concentration of N‐acetyl‐L‐aspartate (NAA) is a
characteristic feature of Canavan disease, a vacuolar leukodystrophy resulting from …

Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of
leukodystrophy caused by mutations in either MLC1 or GLIALCAM genes. Previous work …

The contribution of an impaired astrocytic K+ regulation system to epileptic neuronal
hyperexcitability has been increasingly recognized in the last decade. A defective K+ …

Megalencephalic leukoencephalopathy with subcortical cysts protein-1 (MLC1) is a
membrane protein expressed by perivascular astrocytes. MLC1 mutations cause MLC, an …

Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare genetic
disorder belonging to the group of vacuolating leukodystrophies. It is characterized by …

Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a type of
leukodystrophy characterized by white matter edema, and it is caused mainly by recessive …