Candida sp. Infections in Patients with Diabetes Mellitus

CF Rodrigues, ME Rodrigues, M Henriques - Journal of clinical medicine, 2019 - mdpi.com
Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Candida Infections of the Genitourinary Tract

JM Achkar, BC Fries - Clinical microbiology reviews, 2010 - Am Soc Microbiol
All humans are colonized with Candida species, mostly Candida albicans, yet some develop
diseases due to Candida, among which genitourinary manifestations are extremely …

Candidalysin is a fungal peptide toxin critical for mucosal infection

DL Moyes, D Wilson, JP Richardson, S Mogavero… - Nature, 2016 - nature.com
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate …

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

S Höfs, S Mogavero, B Hube - Journal of microbiology, 2016 - Springer
The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Adhesins in human fungal pathogens: glue with plenty of stick

PWJ de Groot, O Bader, AD de Boer, M Weig… - Eukaryotic …, 2013 - Am Soc Microbiol
Understanding the pathogenesis of an infectious disease is critical for developing new
methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to …

Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition

L Mukaremera, KK Lee, HM Mora-Montes… - Frontiers in …, 2017 - frontiersin.org
Candida albicans is a human opportunist pathogen that can grow as yeast, pseudohyphae,
or true hyphae in vitro and in vivo, depending on environmental conditions. Reversible …

Candida albicans Cell Wall Proteins

WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells

QT Phan, CL Myers, Y Fu, DC Sheppard… - PLoS …, 2007 - journals.plos.org
Candida albicans is the most common cause of hematogenously disseminated and
oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of …

Candida albicans Als3, a multifunctional adhesin and invasin

Y Liu, SG Filler - Eukaryotic cell, 2011 - Am Soc Microbiol
Candida albicans is part of the normal human flora, and it grows on mucosal surfaces in
healthy individuals. In susceptible hosts, this organism can cause both mucosal and …