Many different approaches have been developed to model and simulate gene regulatory
networks. We proposed the following categories for gene regulatory network models …

SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …

Erythroid cell production results from passage through cellular hierarchies dependent on
differential gene expression under the control of transcription factors responsive to changing …

Full exploitation of microarray data requires hidden information that cannot be extracted
using current analysis methodologies. We present a new approach, hidden variable …

Abstract The Arabidopsis Co-expression Tool, ACT, ranks the genes across a large
microarray dataset according to how closely their expression follows the expression of a …

High-throughput technologies are generating large amounts of complex data that have to be
stored in databases, communicated to various data analysis tools and interpreted by …

Nature exhibits modular design in biological systems. Gene module level analysis is based
on this module concept, aiming to understand biological network design and systems …

DNA-binding transcription factors bind to promoters that carry their binding sites.
Transcription factors therefore function as nodes in gene regulatory networks. In the present …

The field of gene expression data analysis has grown in the past few years from being
purely data-centric to integrative, aiming at complementing microarray analysis with data …

Embryonic development and adult tissue homeostasis are controlled through activation of
intracellular signal transduction pathways by extracellular growth factors. In the past, signal …